Non-orthogonal kV imaging guided patient position verification in non-coplanar radiation therapy with dataset-free implicit neural representation.

Journal: Medical physics
Published Date: May 19, 2025

Abstract

BACKGROUND: Cone-beam CT (CBCT) is crucial for patient alignment and target verification in radiation therapy (RT). However, for non-coplanar beams, potential collisions between the treatment couch and the on-board imaging system limit the range that the gantry can be rotated. Limited-angle measurements are often insufficient to generate high-quality volumetric images for image-domain registration, therefore limiting the use of CBCT for position verification. An alternative to image-domain registration is to use a few 2D projections acquired by the onboard kV imager to register with the 3D planning CT for patient position verification, which is referred to as 2D-3D registration.

Authors

  • Siqi Ye
    Department of Radiation Oncology, Stanford University, Stanford, CA, 94305, United States of America.
  • Yizheng Chen
    Department of Radiation Oncology, Stanford University, Stanford, 94305, USA.
  • Siqi Wang
    School of Mechanical Engineering and Automation, Beihang University, Beijing, 100191, People's Republic of China.
  • Lei Xing
    Department of Radiation Oncology, Stanford University, CA, USA.
  • Yu Gao
    Department of Radiology Center, The First Affiliated Hospital of Xinxiang Medical University, Xin Xiang, China.

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