Right Ventricular Strain as a Key Feature in Interpretable Machine Learning for Identification of Takotsubo Syndrome: A Multicenter CMR-based Study.

Journal: Academic radiology
Published Date:

Abstract

RATIONALE AND OBJECTIVES: To develop an interpretable machine learning (ML) model based on cardiac magnetic resonance (CMR) multimodal parameters and clinical data to discriminate Takotsubo syndrome (TTS), acute myocardial infarction (AMI), and acute myocarditis (AM), and to further assess the diagnostic value of right ventricular (RV) strain in TTS.

Authors

  • Zeliu Du
    Zhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Key Laboratory of Precision Medicine of Lishui City, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.); Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.).
  • Hongfei Hu
    Zhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Key Laboratory of Precision Medicine of Lishui City, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.); Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.).
  • Chenqi Shen
    Zhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Key Laboratory of Precision Medicine of Lishui City, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.); Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.).
  • Jie Mei
    Department of Neurology and Department of Experimental Neurology, Neurocure Cluster of Excellence, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
  • Ye Feng
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing 100071, China.
  • Yechao Huang
    Zhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Key Laboratory of Precision Medicine of Lishui City, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.); Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.).
  • Xinyu Chen
    State Key Laboratory of ASIC and System, School of Microelectronics, Fudan University, Shanghai 200433, China.
  • Xinyu Guo
    Keya Medical Co., Ltd, Longong, Shenzhen, China. Electronic address: xinyug@keyamedical.com.
  • Zhanning Hu
    Zhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Key Laboratory of Precision Medicine of Lishui City, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.); Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.).
  • Liyan Jiang
    Department of Respiration, Shanghai Chest Hospital, Shanghai, China.
  • Yanping Su
    Zhejiang Key Laboratory of Imaging and Interventional Medicine, Zhejiang Engineering Research Center of Interventional Medicine Engineering and Biotechnology, Key Laboratory of Precision Medicine of Lishui City, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.); Department of Radiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, China (Z.D., H.H., C.S., J.M., Y.F., Y.H., X.C., X.G., Z.H., L.J., Y.S., J.J., C.L.).
  • Jumatay Biekan
    Circle Cardiovascular Imaging, Calgary, AB, Canada (J.B.).
  • Lingchun Lyv
    Department of Cardiovascular Medicine, Lishui Hospital, Zhejiang University, Lishui 323000, China (L.L.).
  • TouKun Chong
    Department of Cardiology, Kiang Wu Hospital, Macao, Special Administrative Region of the People's Republic of China (T.C.).
  • Cunxue Pan
    Department of Radiology, Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai 519000, China (C.P.).
  • Kan Liu
    Department of Urology, Hunan Cancer Hospital, Changsha, Hunan, China.
  • Jiansong Ji
    Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Lishui Hospital of Zhejiang University, Lishui 323000, China.
  • Chenying Lu
    Departments of Medicine and Radiology, State University of New York, Upstate Medical University Hospital, Syracuse, USA.

Keywords

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