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Improving image quality on pediatric and neonatal radiography using AI-based compensation for image degradation.

Japanese journal of radiology
PURPOSE: To evaluate the impact of an AI-based, noise reduction technique for compensation of image degradation on pediatric and neonatal chest and abdomen radiography using a visual grading analysis.

A neural network approach to glomerular filtration rate estimation: a single-centre retrospective audit.

Nuclear medicine communications
OBJECTIVES: The 2009 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation without race correction factor is frequently used for an estimate of glomerular filtration rate (eGFR) and to support a single-sample GFR regime. This study exa...

AI-Driven Detection and Measurement of Keratinized Gingiva in Dental Photographs: Validation Using Reference Retainers.

Journal of clinical periodontology
AIM: To evaluate a deep learning (DL) model for detecting keratinized gingiva (KG) in dental photographs and validate its clinical applicability using reference retainers for calibration.

A vaccine chatbot intervention for parents to improve HPV vaccination uptake among middle school girls: a cluster randomized trial.

Nature medicine
Conversational artificial intelligence, in the form of chatbots powered by large language models, offers a new approach to facilitating human-like interactions, yet its efficacy in enhancing vaccination uptake remains under-investigated. This study a...

Combining multi-omics analysis with machine learning to uncover novel molecular subtypes, prognostic markers, and insights into immunotherapy for melanoma.

BMC cancer
BACKGROUND: Melanoma (SKCM) is an extremely aggressive form of cancer, characterized by high mortality rates, frequent metastasis, and limited treatment options. Our study aims to identify key target genes and enhance the diagnostic accuracy of melan...

CNRein: an evolution-aware deep reinforcement learning algorithm for single-cell DNA copy number calling.

Genome biology
Low-pass single-cell DNA sequencing technologies and algorithmic advancements have enabled haplotype-specific copy number calling on thousands of cells within tumors. However, measurement uncertainty may result in spurious CNAs inconsistent with real...

Prediction of new-onset migraine using clinical-genotypic data from the HUNT Study: a machine learning analysis.

The journal of headache and pain
BACKGROUND: Migraine is associated with a range of symptoms and comorbid disorders and has a strong genetic basis, but the currently identified risk loci only explain a small portion of the heritability, often termed the "missing heritability". We ai...

Assessment of the long RR intervals using convolutional neural networks in single-lead long-term Holter electrocardiogram recordings.

Scientific reports
Advancements in medical technology have extended long-term electrocardiogram (ECG) monitoring from the traditional 24 h to 7-14 days, significantly enriching ECG data. However, this poses unprecedented challenges for physicians in analyzing these ext...

Validation of body composition parameters extracted via deep learning-based segmentation from routine computed tomographies.

Scientific reports
Sarcopenia and body composition metrics are strongly associated with patient outcomes. In this study, we developed and validated a flexible, open-access pipeline integrating available deep learning-based segmentation models with pre- and postprocessi...

Transformer-based deep learning ensemble framework predicts autism spectrum disorder using health administrative and birth registry data.

Scientific reports
Early diagnosis and access to resources, support and therapy are critical for improving long-term outcomes for children with autism spectrum disorder (ASD). ASD is typically detected using a case-finding approach based on symptoms and family history,...