Computer methods and programs in biomedicine
Jan 11, 2018
BACKGROUND AND OBJECTIVE: The application of medical knowledge strongly affects the performance of intelligent diagnosis, and method of learning the weights of medical knowledge plays a substantial role in probabilistic graphical models (PGMs). The p...
The international journal of medical robotics + computer assisted surgery : MRCAS
Jan 10, 2018
BACKGROUND: In image-guided robotic interventions, an error component is related to the positioning error of the manipulator. Therefore, measuring the kinematic error is required during robot development. However, no specialized measurement device ex...
Journal of chemical information and modeling
Jan 10, 2018
Inspired by natural language processing techniques, we here introduce Mol2vec, which is an unsupervised machine learning approach to learn vector representations of molecular substructures. Like the Word2vec models, where vectors of closely related w...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 5, 2018
As one of the most challenging tasks in sequence analysis, protein remote homology detection has been extensively studied. Methods based on discriminative models and ranking approaches have achieved the state-of-the-art performance, and these two kin...
Computational and mathematical methods in medicine
Jan 4, 2018
Human heart electrophysiology is complex biological phenomenon, which is indirectly assessed by the measured ECG signal. ECG trace is further analyzed to derive interpretable surrogates including QT interval, QRS complex, PR interval, and T wave morp...
Real-time detection of seizure activity in epilepsy patients is critical in averting seizure activity and improving patients' quality of life. Accurate evaluation, presurgical assessment, seizure prevention, and emergency alerts all depend on the rap...
International journal of molecular medicine
Jan 2, 2018
Colorectal cancer (CRC) is one of the most common cancers and a major cause of mortality. The present study aimed to identify potential biomarkers for CRC metastasis and uncover the mechanisms underlying the etiology of the disease. The five datasets...
Database : the journal of biological databases and curation
Jan 1, 2018
OBJECTIVE: A major challenge in precision medicine is the development of patient-specific genetic biomarkers or drug targets. The firsthand information of the genes associated with the pathologic pathways of interest is buried in the ocean of biomedi...
Database : the journal of biological databases and curation
Jan 1, 2018
In this paper, we describe a hierarchical bi-directional attention-based Re-current Neural Network (RNN) as a reusable sequence encoder architecture, which is used as sentence and document encoder for document classification. The sequence encoder is ...
Frontiers in bioscience (Landmark edition)
Jan 1, 2018
Early diagnosis is playing an important role in preventing progress of the Alzheimer's disease (AD). This paper proposes to improve the prediction of AD with a deep 3D Convolutional Neural Network (3D-CNN), which can show generic features capturing A...
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