AIMC Topic: Valine
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Ritonavir-boosted paritaprevir, ombitasvir plus ribavirin could improve eGFR in patients with renal impairment and HCV: an Egyptian cohort.
Expert review of gastroenterology & hepatology
Nov 13, 2018
BACKGROUND: The present study aimed at evaluation of changes in estimated glomerular filtration rate (eGFR) among chronic Hepatitis C virus (HCV) patients with chronic kidney disease (CKD) Stages 3-5 who were treated with 12 weeks of ritonavir-booste...
Renal Dialysis
Viral Load
Time Factors
Sustained Virologic Response
Antiviral Agents
Sulfonamides
Genotype
Hepacivirus
Anilides
Kidney
Proline
Carbamates
Aged
Drug Therapy, Combination
Lactams, Macrocyclic
Young Adult
Hepatitis C, Chronic
Macrocyclic Compounds
Humans
Adult
Valine
Ribavirin
Prospective Studies
Male
Renal Insufficiency, Chronic
Female
Middle Aged
Treatment Outcome
Glomerular Filtration Rate
Cyclopropanes
Recovery of Function
Egypt
UPLC-MS/MS method for the simultaneous quantification of sofosbuvir, sofosbuvir metabolite (GS-331007) and daclatasvir in plasma of HIV/HCV co-infected patients.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dec 12, 2017
Direct-acting antiviral agents (DAAs) represent the major advance in hepatitis C virus (HCV) infection treatment leading to extremely high eradication rates in HCV mono- and HIV/HCV co-infected patients. In this scenery, availability of Therapeutic D...
GC-MS Metabolomics Identifies Metabolite Alterations That Precede Subclinical Mastitis in the Blood of Transition Dairy Cows.
Journal of proteome research
Nov 28, 2016
The objectives of this study were to determine alterations in the serum metabolites related to amino acid (AA), carbohydrate, and lipid metabolism in transition dairy cows before diagnosis of subclinical mastitis (SCM), during, and after diagnosis of...
Ombitasvir, paritaprevir, and ritonavir plus ribavirin for chronic hepatitis C virus genotype 4 infection in Egyptian patients with or without compensated cirrhosis (AGATE-II): a multicentre, phase 3, partly randomised open-label trial.
The lancet. Gastroenterology & hepatology
Jun 16, 2016
BACKGROUND: In Egypt, chronic hepatitis C virus (HCV) infection occurs in around 10% of the population (about 8 million individuals), and is a leading cause of liver cirrhosis, hepatocellular carcinoma, and mortality. Although HCV genotype 4 constitu...
Sustained Virologic Response
Anilides
Carbamates
Lactams, Macrocyclic
Macrocyclic Compounds
Ribavirin
Cyclopropanes
Egypt
Sulfonamides
Hepacivirus
Administration, Oral
Proline
Ritonavir
Drug Therapy, Combination
Humans
Hepatitis C, Chronic
Female
Valine
Adolescent
Aged
Drug Administration Schedule
Aged, 80 and over
Antiviral Agents
Young Adult
Genotype
Adult
Liver Cirrhosis
Male
Treatment Outcome
Middle Aged
Follow-Up Studies
Ombitasvir, paritaprevir, and ritonavir plus ribavirin in adults with hepatitis C virus genotype 4 infection and cirrhosis (AGATE-I): a multicentre, phase 3, randomised open-label trial.
The lancet. Gastroenterology & hepatology
Jun 16, 2016
BACKGROUND: Hepatitis C virus (HCV) genotype 4 infection is most commonly reported in sub-Saharan Africa and the Middle East; however, prevalence is increasing worldwide through immigration. HCV genotype 4 accounts for 20% of all infections, but clin...
Humans
Female
Aged
Aged, 80 and over
Young Adult
Treatment Outcome
Follow-Up Studies
Cyclopropanes
Sulfonamides
Hepacivirus
Proline
Adult
Male
Middle Aged
Adolescent
Antiviral Agents
Genotype
Anilides
Ritonavir
Carbamates
Drug Therapy, Combination
Lactams, Macrocyclic
Hepatitis C, Chronic
Macrocyclic Compounds
Valine
Ribavirin
Drug Administration Schedule
Sustained Virologic Response
DeepHisCoM: deep learning pathway analysis using hierarchical structural component models.
Briefings in bioinformatics
Sep 20, 2022
Many statistical methods for pathway analysis have been used to identify pathways associated with the disease along with biological factors such as genes and proteins. However, most pathway analysis methods neglect the complex nonlinear relationship ...
PycnoRacer®, a fitness drink including Pycnogenol®, improves recovery and training in the Cooper test.
Panminerva medica
Dec 1, 2019
BACKGROUND: This study evaluates the effects of training (on running distance measured with a Cooper test) in 3 weeks in non-professional athletes using PycnoRacer®, a fitness drink (FD) including Pycnogenol® during the training period.
[A real-world study of paritaprevir/ritonavir-ombitasvir combined with dasabuvir in the treatment of genotype 1b chronic hepatitis C].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
Dec 20, 2018
To recognize the efficacy and safety of paritaprevir/ritonavir-ombitasvir combined with dasabuvir (OBV/PTV/RTV+DSV) in the treatment of genotype 1b chronic hepatitis C. Patients with genotype 1b chronic hepatitis C who were admitted to the People's...
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