AI Medical Compendium

Highly multiplexed mammalian metabolic engineering with a shotgun approach.

Nature biotechnology Oct 6, 2026

Mammalian metabolic engineering advances basic biology, bioproduction and cell therapy. However, as pathway complexity increases, so does the size of the combinatorial design space and required DNA constructs, rendering unbiased screens intractable. ... read more

Development and Validation of an Interpretable Machine Learning Model Based on Gd-EOB-DTPA-enhanced MRI for Evaluating Small HCC (≤2 cm): A Multicenter Cohort Study.

Academic radiology Oct 6, 2026

RATIONALE AND OBJECTIVES: This study aims to develop and externally validate an interpretable machine-learning model that integrates gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid magnetic resonance imaging (MRI) radiomics, qualitative M... read more

Decoding systemic vascular health and hypertensive disorders in pregnancy through retinal imaging and Visionary AI.

Nature biotechnology Oct 6, 2026

Hypertensive disorders of pregnancy arise from early placental and systemic vascular dysfunction, yet current first-trimester screening remains imprecise, biologically opaque and logistically challenging. Here we present Visionary AI, an interpretabl... read more

How does AI-generated assessment compare to expert assessment in simulation-based experiences: Analyzing AI-human interrater reliability.

Advances in simulation (London, England) Oct 7, 2026

BACKGROUND: In the health professions, artificial intelligence simulation-based experiences (AI-SBEs) are increasingly used to evaluate learner performance and provide feedback. Benefits of AI-SBEs include providing instantaneous feedback, allowing m... read more

Advances in Indocyanine Green Near-Infrared Fluorescence for Extrahepatic Biliary Identification in Laparoscopic Cholecystectomy for Acute Cholecystitis: A Narrative Review.

Medical science monitor : international medical journal of experimental and clinical research Oct 7, 2026

Laparoscopic cholecystectomy, a minimally invasive procedure with rapid recovery, remains the standard surgical intervention for acute cholecystitis. Acute inflammation of the gallbladder can cause severe edema, dense adhesions, and anatomical distor... read more

Automated pharmacophore hypothesis generator for SILCS-Pharm: ph4gen.

Journal of computer-aided molecular design Oct 7, 2026

Here we present ph4gen, a tool for the automated generation of pharmacophore hypotheses developed for use with the site identification by ligand competitive saturation (SILCS) technology. It builds upon the previously established SILCS-Pharm approach... read more

Silver doping induced fluorescence enhancement of gold nanoclusters combined with machine learning for detection of quercetin.

Analytical and bioanalytical chemistry Oct 7, 2026

A novel fluorescence sensing method of quercetin (Que) was constructed based on gold and silver bimetallic nanoclusters (L-Cys@Au-Ag NCs) that were prepared by sonochemical synthesis. In comparison with gold nanoclusters, the bimetallic nanoclusters ... read more

g-C3N4-based hybrid photocatalysts for removal of emerging pharmaceutical pollutants from water: recent advances, degradation pathways, toxicity assessment,and future perspectives.

Environmental geochemistry and health Oct 7, 2026

Pharmaceutical pollutants (PPs) are increasingly detected in aquatic environments, raising concerns about their persistence and potential risks to human health and ecosystems. Advanced oxidation processes based on photocatalysis have been widely deve... read more

Revolutionizing Pancreatic Cancer Detection: The Role of AI-Integrated Biosensors in Early Diagnostics.

Advances in biochemical engineering/biotechnology Oct 7, 2026

Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is among the most aggressive malignancies, often progresses silently until advanced stages, which significantly contributes to high mortality rates. The development of biosensor... read more

α7 integrin co-regulates chromatin accessibility and gene expression in HPV-negative head and neck cancer.

Signal transduction and targeted therapy Oct 7, 2026

Epigenetic regulation and gene transcription are dynamically modulated by extracellular signals, including focal adhesions; however, the role of integrins in these processes remains poorly understood. In this study in HPV-negative head and neck squam... read more

Artificial Intelligence Medical Compendium