AIMC Topic: Brain

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Predictive models of influenza A virus lethal disease yield insights from ferret respiratory tract and brain tissues.

Scientific reports Jul 8, 2025
Collection of systemic tissues from influenza A virus (IAV)-infected ferrets at a fixed timepoint post-inoculation represents a frequent component of risk assessment activities to assess the capacity of IAV to replicate systemically. However, few stu...
Humans Lung Influenza A virus Disease Models, Animal Virus Replication Machine Learning Brain Animals Respiratory System Ferrets Orthomyxoviridae Infections
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Enhanced particle swarm optimization for feature selection in SVM-based Alzheimer's disease diagnosis.

Scientific reports Jul 7, 2025
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder marked by neuronal loss, leading to cognitive and behavioral decline. With the aging global population, AD incidence and its socioeconomic burden are increasing. Developing effectiv...
White Matter Female Particle Swarm Optimization Humans Aged Alzheimer Disease Male Algorithms Gray Matter Support Vector Machine Brain Magnetic Resonance Imaging
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Assessing changes in whole-brain structural connectivity in the unilateral 6-hydroxydopamine rat model of Parkinson's disease using diffusion imaging and tractography.

Journal of neural engineering Jul 7, 2025
Parkinson's disease (PD) is a multifactorial, progressive neurodegenerative disease that has a profound impact on those it afflicts. Its hallmark pathophysiology is characterized by degeneration of dopaminergic (DA) neurons in the midbrain which trig...
Animals Male Rats Rats, Sprague-Dawley Brain Nerve Net Disease Models, Animal Diffusion Magnetic Resonance Imaging Parkinson Disease Diffusion Tensor Imaging Neural Pathways Oxidopamine
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Neuroimaging and biological markers of different paretic hand outcomes after stroke.

Journal of neuroengineering and rehabilitation Jul 5, 2025
BACKGROUND: Hand dysfunction significantly affects independence after stroke, with outcomes varying across individuals. Exploring biomarkers associated with the paretic hand can improve the prognosis and guide personalized rehabilitation. However, wh...
Stroke Neuroimaging Paresis Middle Aged Magnetic Resonance Imaging Hand Humans Biomarkers Brain Adult Male Female Aged
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Machine learning-based prognostic prediction for acute ischemic stroke using whole-brain and infarct multi-PLD ASL radiomics.

BMC medical imaging Jul 4, 2025
INTRODUCTION: Accurate early prognostic prediction for acute ischemic stroke (AIS) is essential for guiding personalized treatment. This study aimed to assess the predictive value of radiomics features from whole-brain and infarct cerebral blood flow...
Radiomics Male Middle Aged Ischemic Stroke Cerebrovascular Circulation Magnetic Resonance Imaging Predictive Value of Tests Prognosis Female Humans Aged Machine Learning Brain
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3BTRON: A Blood-Brain Barrier Recognition Network.

Communications biology Jul 4, 2025
The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis. During ageing, the BBB undergoes structural alterations. Electron microscopy (EM) is the gold standard for studying the structural alterations of the brain vasculatu...
Mice Mice, Inbred C57BL Male Microscopy, Electron Aging Deep Learning Image Processing, Computer-Assisted Brain Blood-Brain Barrier Animals
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Intrinsic dynamic shapes responses to external stimulation in the human brain.

eLife Jul 3, 2025
Sensory stimulation of the brain reverberates in its recurrent neural networks. However, current computational models of brain activity do not separate immediate sensory responses from this intrinsic dynamic. We apply a vector-autoregressive model wi...
Acoustic Stimulation Nerve Net Photic Stimulation Male Female Eye Movements Adult Models, Neurological Humans Brain
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Influence of cognitive networks and task performance on fMRI-based state classification using DNN models.

Scientific reports Jul 3, 2025
Deep neural networks (DNNs) excel at extracting insights from complex data across various fields, however, their application in cognitive neuroscience remains limited, largely due to the lack of approaches with interpretability. Here, we employ two d...
Magnetic Resonance Imaging Humans Female Memory, Short-Term Adult Task Performance and Analysis Neural Networks, Computer Young Adult Male Brain Cognition
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Universal dimensions of visual representation.

Science advances Jul 2, 2025
Do visual neural networks learn brain-aligned representations because they share architectural constraints and task objectives with biological vision or because they share universal features of natural image processing? We characterized the universal...
Humans Magnetic Resonance Imaging Neural Networks, Computer Vision, Ocular Brain Mapping Brain Visual Perception Image Processing, Computer-Assisted
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A dual path graph neural network framework for dementia diagnosis.

Scientific reports Jul 2, 2025
Dementia typically results from damage to neural pathways and the consequent degeneration of neuronal connections. Graph neural networks (GNNs) have been widely employed to model complex brain networks. However, leveraging the complementary temporal,...
Nerve Net Graph Neural Networks Brain Humans Dementia Neural Networks, Computer Magnetic Resonance Imaging Algorithms
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