Recent advances in artificial intelligence (AI) have raised interest in its potential to similarly progress biological psychiatry. This study investigates the current utility of AI models in predicting psychiatric phenotypes in youth - a critical win... read more
T-lineage acute lymphoblastic leukemia (T-ALL) is an aggressive pediatric malignancy characterized by complex heterogeneity across multiple molecular layers. Accurate subtyping is essential for understanding disease mechanisms, risk stratification, a... read more
The inflammatory decidual reaction renders the cycling endometrium transiently permissive for embryo implantation before transforming it into the decidua, the maternal bed accommodating the fetal placenta during pregnancy. Disruptions in decidual tis... read more
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract, yet GIST-specific omics evidence remains scattered across small cohorts and is not represented as a dedicated disease project in major ca... read more
Driven by the rise of antimicrobial resistance, antimicrobial peptides (AMPs) have emerged as promising therapeutics capable of targeting multidrug-resistant pathogens. Because identifying AMPs and their specific targets requires costly and labor-int... read more
Single-particle cryo-electron microscopy (cryo-EM) reveals structural heterogeneity in macromolecular complexes, but recovering continuous conformational landscapes at high resolution remains challenging. Here, we introduce CryoARC, a deep learning f... read more
Fixed larval specimens often shrink and curve, making length measurement labor-intensive. Although recent studies have demonstrated efficient fish-length estimation from images using deep learning, methods for estimating curved length remain limited.... read more
Recent advances in neuroscience have highlighted the central role of glial cells, particularly astrocytes, in regulating neural network activity through calcium-dependent neuron-glia communication. In parallel, nanostructured cluster-assembled materi... read more
Hibernating bears show remarkable metabolic suppression. Their decline in core body temperature (Tb) is moderate(from 38{degrees}C to 30-35{degrees}C), but their metabolism declines as much as 75%. To understand the role of sleep in this hypometaboli... read more
Objectives: The aim of mammographic screening is the early detection of invasive cancers. In the era of artificial intelligence (AI), this tool may improve diagnosis of earlier stages. The purpose of this study was to assess the impact on selected qu... read more
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