Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 10,641 to 10,650 of 209,601 articles

Association of a polygenic risk score with coronary atherosclerotic burden in clinical CT angiograms

medRxiv
Background: Polygenic risk scores (PRS) for coronary artery disease (CAD) are associated with cardiovascular events, but the relationship between inherited risk and routinely reported coronary computed tomography angiography (CTA) findings has not be... read more 

Can Large Language Models Diagnose Primary Immunodeficiency from Patient-Described Symptoms?

medRxiv
Patients with primary immunodeficiency (PID) often face prolonged diagnostic delays and may increasingly turn to large language models (LLMs) to interpret their symptoms during this period. We evaluated whether an LLM could recognize PID from symptom... read more 

AI Adoption for NCDs in Kenya: A Qualitative Study

medRxiv
Background: Non-communicable diseases (NCDs) represent a critical public health challenge in Kenya, responsible for over 50% of inpatient admissions and 40% of deaths. While digital health tools and artificial intelligence offer promising ways to imp... read more 

Deriving OCT-Equivalent Retinal Nerve Fiber Layer Thickness Maps from Fundus Photographs with Deep Learning Improves Glaucoma Diagnosis

medRxiv
Purpose: To develop and evaluate a deep learning model that predicts optical coherence tomography (OCT)-equivalent retinal nerve fiber layer thickness (RNFLT) maps directly from color fundus photographs and to assess their diagnostic value for glauco... read more 

Deep Learning Prediction of Personalized Peripapillary Retinal Nerve Fiber Layer Thickness Norms from Fundus Images in Glaucoma

medRxiv
Purpose: To predict retinal nerve fiber layer thickness (RNFLT) norms from fundus images. Methods: We selected 18,000 OCT scans and visual fields (VF) from the Massachusetts Eye and Ear Glaucoma Service. A U-Net-based deep learning model was develope... read more 

Future Pandemics: AI-Designed Diagnostic Assays for Detection of Andes Orthohantavirus (ANDV) Associated with the 2026 MV Hondius Outbreak

medRxiv
Andes orthohantavirus (ANDV), the primary etiological agent of hantavirus pulmonary syndrome (HPS) in South America, is uniquely capable of limited human-to-human transmission, posing a significant challenge for outbreak control. Recent events, inclu... read more 

An ECG foundation model for generalizable cardiac function prediction across the lifespan

medRxiv
Background Artificial intelligence-enhanced electrocardiography (AI-ECG) enables scalable, low-cost cardiac dysfunction screening, but existing models are annotation-intensive and predominantly adult-derived, leaving paediatric generalizability uncer... read more 

Interconnecting ADC Structure with Tumor Cell Biology with Multimodal Learning

bioRxiv
Antibody-drug conjugates (ADCs) represent a significant advancement in cancer therapy, yet their development remains constrained by high attrition rates driven by an incomplete understanding of how ADC chemical design interconnects with tumor biology... read more 

Data-Constrained Recurrent Network Neural Model Uncovers the Circuit Mechanism of Olfactory OFF Responses

bioRxiv
Sensory neural circuits must encode both the presence and termination of a stimulus. Following odor offset, projection neurons (PNs) in the insect antennal lobe (AL) exhibit transient increases in firing rate, termed OFF responses, yet the circuit me... read more 

Sequence-independent protein domain detection and classification with PRISM

bioRxiv
The explosion of predicted protein structures has revealed countless novel domain families. However, gold-standard segmentation tools like Chainsaw and Merizo are trained on rapidly obsoleting CATH databases, lack automatic domain classification, and... read more