Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 10,651 to 10,660 of 209,601 articles

GraphTox: A Semi-Supervised Pre-Trained Framework for Peptide Toxicity Prediction using Geometric Graph Transformer and LORA-Based Finetuning

bioRxiv May 27, 2026
Peptides are widely used as potential therapeutic agents in drug discovery and biotechnology because they are specific, effective, and relatively inexpensive to produce. They are used in drug development, vaccines, and antimicrobial treatments. Howev... read more 
bioinformatics

An AI-agent-orchestrated grey-box Transformer framework for sparse pharmacokinetic curve reconstruction and pharmacometric model initialization

bioRxiv May 27, 2026
Clinical pharmacokinetic (PK) modelling is constrained by sparse sampling, limited generalisability of single-drug models, and labour-intensive workflows, making it difficult to infer complete drug exposure from limited concentration observations. We... read more 
pharmacology and toxicology

An LSEC-focused computational drug repurposing platform for liver fibrosis: Identification of vorinostat and other LSEC-protective candidates

bioRxiv May 27, 2026
Liver sinusoidal endothelial cells (LSECs) are increasingly recognized as a critical yet underexplored cell type in anti-fibrotic drug development. This study presents a computational drug screening platform integrating LSEC-specific transcriptomic a... read more 
pharmacology and toxicology

A scutum-focused deep learning pipeline for species-level identification of Aedes aegypti and Aedes albopictus from citizen-science images

bioRxiv May 27, 2026
Background. Mosquito-borne diseases transmitted by Aedes aegypti and Aedes albopictus, including dengue, Zika, chikungunya, and yellow fever, depend critically on rapid and accurate vector identification. Although deep learning has achieved high accu... read more 
bioinformatics

Investigating Hybrid Deep Learning Architectures for Speech Envelope Reconstruction from EEG

bioRxiv May 27, 2026
Reconstructing speech envelopes from electroencephalography(EEG) signals is a challenging but valuable task for brain-computer interfaces (BCIs), with applications in assistive communication for individuals with speech impairments. While deep learnin... read more 
neuroscience

Deep learning-based decoding of axonal ultrastructure in gene-edited mice using electron microscopy imaging

bioRxiv May 27, 2026
Myelin forms an insulating sheath around axons enabling both rapid and energy-efficient conduction of action potentials and myelin abnormalities or loss can lead to severe motor, sensory, and cognitive impairment. While electron microscopy can resolv... read more 
neuroscience

Affinity Fine-Tuning of Boltz-2: An Open Framework for Protein-Ligand Potency Prediction in Drug Discovery

bioRxiv May 27, 2026
Boltz-2 has enabled accurate binding affinity prediction by leveraging co-folded protein-ligand structures, but the absence of a public training recipe has limited its use in active drug discovery projects, where new experimental measurements and con... read more 
molecular biology

Protracted prediction: Neurodevelopment of reward processing in the adolescent cerebellum.

bioRxiv May 27, 2026
Adolescence is characterized by heightened reward sensitivity, novelty seeking, and risky decision-making. Prevailing neurodevelopmental frameworks typically attribute these behavioral trends to a maturational imbalance between rapidly developing str... read more 
neuroscience

Inhibition benefits neural system identification

bioRxiv May 27, 2026
Neural system identification approaches use empirical data to fit the stimulus-response functions of neurons. Augmented by deep neural networks, such models have achieved high predictive performance and allow to perform in silico experiments to test ... read more 
neuroscience

Distinct afferent signatures onto anterior and posterior VMHvl subdomains and their progesterone receptor-expressing neurons

bioRxiv May 27, 2026
Female sexual behavior is fundamentally coupled to reproductive state, requiring the dynamic and coordinated regulation of sexual receptivity and rejection across the estrous cycle. In mice, these opposing behaviors are controlled by distinct neurona... read more 
neuroscience
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