Understanding and modeling how a single human genome concurrently encodes gene regulatory programs for thousands of cell types remains a central challenge in genomics and machine learning. Most human cell types emerge during embryonic, fetal, and ped... read more
Foundation models and deep learning systems are increasingly proposed as core components of "virtual cells" capable of forecasting transcriptomic responses to unseen perturbations. Yet rigorous evaluation of perturbation prediction in high-dimensiona... read more
Covering: 2020 to 2025Natural products are a major source of bioactive compounds, yet elucidating their biosynthetic pathways remains a major challenge due to complex genotype-phenotype relationships. Recent advances in computational approaches, part... read more
BACKGROUND: False-positive (FP) alerts from implantable loop recorders increase clinical workload and may delay appropriate intervention. AccuRhythm AI, a cloud-based filtering algorithm, is designed to reduce these alerts in Reveal LINQ and LINQ II ... read more
In stereotactic body radiotherapy for bone metastases using the CyberKnife system, spinal anatomy is generally employed as the alignment reference. However, when treating pelvic tumors such as those in the pubic bone or proximal femur, the spinal ref... read more
BACKGROUND: YouTube is increasingly used for healthcasting, the sharing of evidence-based dietary and lifestyle interventions by domain experts. In the metabolic health domain, channels focused on therapeutic carbohydrate restriction have accumulated... read more
Understanding human gaze behavior is essential for complex scene comprehension and human-computer interaction. Traditional gaze following models are typically restricted to pure spatial localization, lacking the high-level capacity to reason about se... read more
Understanding the effects of interventions is central to scientific progress, with randomized controlled trials (RCTs) regarded as the gold standard for causal inference in many applied fields. However, RCTs are costly, time-consuming, and often cons... read more
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