The effectiveness of convolutional neural networks in medical image segmentation relies on large-scale, high-quality annotations, which are costly and time-consuming to obtain. Even expert-labeled datasets inevitably contain noise arising from subjec... read more
Journal of molecular graphics & modelling
May 26, 2026
VEGFR-2 is an important target for oncological interventions due to its key role in angiogenesis, a biological process vital for tumour expansion and metastasis. The targeted blockade of VEGFR-2 has emerged as a promising treatment approach across a ... read more
Objective.Current robotic prostheses developed for individuals with transradial amputation often lack physiological feedback, particularly proprioceptive information, which limits control precision and increases reliance on vision.Approach.This study... read more
The application of Large Language Models (LLMs) and Transformers to biological and healthcare datasets requires the extraction of highly accurate, noise-filtered ecological networks. The Random Effects Model (REM) is a powerful statistical method for... read more
Hibernating bears show remarkable metabolic suppression. Their decline in core body temperature (Tb) is moderate(from 38{degrees}C to 30-35{degrees}C), but their metabolism declines as much as 75%. To understand the role of sleep in this hypometaboli... read more
Single-particle cryo-electron microscopy (cryo-EM) reveals structural heterogeneity in macromolecular complexes, but recovering continuous conformational landscapes at high resolution remains challenging. Here, we introduce CryoARC, a deep learning f... read more
Fixed larval specimens often shrink and curve, making length measurement labor-intensive. Although recent studies have demonstrated efficient fish-length estimation from images using deep learning, methods for estimating curved length remain limited.... read more
Recent advances in neuroscience have highlighted the central role of glial cells, particularly astrocytes, in regulating neural network activity through calcium-dependent neuron-glia communication. In parallel, nanostructured cluster-assembled materi... read more
Cells that store lipids for other cells or organs can contain ''giant'' or large lipid droplets (LLDs) greater than 2 m in diameter. In this study, human postmortem choroid plexus was evaluated for lipid droplets. Staining with hematoxylin and eosin ... read more
Artificial intelligence and machine learning for computer vision (CV) and image recognition is a rapidly evolving field with multiple potential applications in plant genomics. While CV has been widely adopted by the research community for plant pheno... read more
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