Genomic foundation models have emerged alongside the rapid progress of large language models, offering a promising framework for learning general-purpose sequence priors for DNA understanding, generation, and design. This connection to LLMs creates a... read more
Surface-enhanced Raman scattering (SERS) nanotags provide highly sensitive platforms for in vitro diagnostics but often require complex, disease-specific customization that limits clinical translation. Biomineralization, in which biomolecules mediate... read more
Background Influenza A virus (IAV) is a major public health burden, causing seasonal epidemics and occasional pandemics. Its transmission from avian species to mammals and subsequent spread requires adaptive changes in the viral genome. Understanding... read more
Tissue-specific chromatin states shape regional mutation density in primary tumors, but whether this relationship persists in metastases is unclear. We integrated whole-genome sequencing data from 2,507 metastatic tumors across six cancer types with ... read more
Tuberculosis remains a leading cause of infectious disease mortality, and the continued emergence of drug-resistant Mycobacterium tuberculosis strains threatens the effectiveness of standard treatment regimens. Culture-based antibiotic susceptibility... read more
While the expansion of spatial omics has revolutionized our ability to dissect tissue architecture, the accumulation of incompatible computational methods has heavily fragmented end-to-end analysis, rendering complex workflows irreproducible. Generic... read more
Thermostability is crucial for protein engineering, but experimental determination of melting temperatures is costly and time-consuming. Most existing machine learning approaches for melting temperature prediction rely on sequential and structural fe... read more
Mandibular reconstruction following segmental resection for oral tumors is a complex procedure necessitating precise restoration of both masticatory function and facial aesthetics. Current Computer-Assisted Surgery (CAS) workflows remain fragmented, ... read more
European journal of cancer (Oxford, England : 1990)
May 25, 2026
INTRODUCTION: Readily available predictive biomarkers for immune checkpoint inhibitor (ICI) response in advanced melanoma are limited. This study evaluates the predictive value of AI-based histopathology analysis. METHODS: Patients with advanced cuta... read more
Journal of infection and public health
May 25, 2026
BACKGROUND: Hand hygiene (HH) is a straightforward yet highly effective preventive measure against healthcare-associated infections; however, global compliance remains suboptimal. This study analyzed a substantial Italian dataset, focusing on adheren... read more
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