Benign prostatic hyperplasia (BPH) is a prevalent age-related disorder characterized by chronic inflammation, metabolic dysregulation, and abnormal cellular proliferation. Protein lactylation, an emerging post-translational modification closely assoc... read more
Titanium alloys are widely used in medical applications, particularly in dentistry and orthopedics, due to their biocompatibility, corrosion resistance, and low density. Electrical Discharge Machining (EDM) offers an effective method for producing mi... read more
The detection and prediction of the condition of machinery and transportation systems in the mining industry are of critical importance due to their direct impact on productivity, maintenance cost reduction, and operational safety. Given the high cos... read more
Sex and gender represent critical yet underutilized precision biomarkers in oncology, influencing cancer incidence, progression, treatment response, and survival outcomes. Biological sex, characterized by chromosomal, hormonal, and anatomical factors... read more
Artificial intelligence (AI) policy for health care is expanding in a fragmented landscape. In a January 1, 2026 snapshot of the Health & AI Policy Index (240 policies), we find that transparency-oriented advisory instruments dominate, equity and saf... read more
Journal of computer-aided molecular design
May 25, 2026
Drug discovery pipelines face persistent challenges, as candidates that show promising results in early laboratory studies are found ineffective in clinical trials-often because their absorption, distribution, metabolism, excretion, and toxicity (ADM... read more
Physical packaging has evolved into a central medium for deep interaction between brands and consumers. While biomimetic design offers cross-disciplinary inspiration for product innovation, there remains a lack of systematic analysis-beyond linear re... read more
Molecular heterogeneity in head and neck squamous cell carcinoma (HNSCC) is well recognized, yet existing subtype frameworks remain largely descriptive and have not translated into therapeutic decision-making. Here, we establish a mechanistic platfor... read more
Acute kidney injury (AKI) is a severe and frequent complication following bee stings, with a reported incidence of 30-50%. Early identification is clinically challenging due to the delayed rise in serum creatinine. This retrospective study aimed to d... read more
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