OBJECTIVE: To develop and validate a clinical-radiomics model based on multiparametric MRI for differentiating solitary primary spinal tumors from solitary spinal metastases. METHODS: This dual-center retrospective study included 510 patients with pa... read more
BACKGROUND: Artificial intelligence (AI) is increasingly recognized as a valuable tool for the early detection and prognosis of oral cancer, addressing the challenge of high mortality due to late diagnosis. Artificial intelligence based diagnostic mo... read more
BMC medical informatics and decision making
May 25, 2026
BACKGROUND: A significant challenge in blood donation is the occurrence of adverse donor reactions (ADRs) and their subsequent negative impact on the blood supply and public health. A promising strategy to mitigate these events is the deployment of n... read more
BACKGROUND: Cell-cell communication (CCC) mediated by ligand-receptor (L-R) interactions is fundamental to deciphering tissue development and disease mechanisms. While single-cell RNA sequencing (scRNA-seq) has advanced this field, existing computati... read more
BACKGROUND: Predicting pathological response to neoadjuvant chemotherapy combined with immunotherapy (NACI) in locally advanced gastric cancer (LAGC) remains challenging. This study aimed to develop a non-invasive predictive model by integrating intr... read more
BACKGROUND: Atrial fibrillation (AF) is a common arrhythmia affecting millions of patients globally. While epigenetic modifications play a significant role in cardiovascular diseases, their contribution to AF remains incompletely understood. Annexin ... read more
BACKGROUND: Timely extubation requires advanced expertise and extensive clinical experience; however, intensive care specialists are scarce globally, and interpreting ventilator graphic monitor waveforms can be challenging for less experienced health... read more
Cancer stem cells (CSCs) drive tumour initiation, progression, metastasis, and therapy resistance through their remarkable plasticity, enabling dynamic transitions between stem-like and differentiated states. A pivotal mechanism underlying this plast... read more
BMC medical informatics and decision making
May 25, 2026
BACKGROUND AND OBJECTIVE: Interpretation of urodynamic studies (UDS) is essential for the assessment of lower urinary tract dysfunction but remains resource-intensive and highly operator-dependent. Artificial intelligence (AI) has increasingly been a... read more
The COVID-19 pandemic showed that heterogeneous antiviral assay designs, endpoints and reporting practices can obscure which candidate drugs and combinations are genuinely promising. As antiviral discovery expands from acute infections to chronic and... read more
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