INTRODUCTION: Fibromyalgia (FM) is a chronic condition characterized by widespread pain and cognitive dysfunction, with pharmacological treatments offering limited efficacy. Although Pain Neuroscience Education (PNE) and therapeutic exercise are evid... read more
Pipeline installation robots install pipelines on both sides of mine roadways using robotic arms; the geometric shape and length of the pipelines affect the movement trajectory of the robotic arms, and the working environment is complex and changeabl... read more
BACKGROUND: Mitochondrial metabolism (MM) abnormalities have been implicated in multiple diseases, but its contribution to sepsis-associated encephalopathy (SAE) remains insufficiently understood. The purpose of this research was to explore the candi... read more
BACKGROUND: Growing evidence indicates that Folate Hydrolase 1 (FOLH1, also known as prostate-specific membrane antigen, PSMA) is aberrantly expressed across multiple malignancies, particularly showing significant upregulation in prostate cancer. How... read more
Access to routine viral load (VL) testing for people living with HIV (PLHIV) remains limited in many low-resource settings. There is a need for pragmatic, data-driven tools that can proactively identify individuals at increased risk of virological fa... read more
INTRODUCTION: Acute febrile illnesses are significant clinical challenge in tropical regions due to overlapping symptomatology among infections such as dengue, scrub typhus, and leptospirosis. This diagnostic dilemma leads to delays in appropriate tr... read more
Diabetes is a common chronic disease that needs early diagnosis and proper management to avoid severe complications. While current Artificial Intelligence (AI) tools generate predictive information, they often lack an integrated element for post-diag... read more
Tomato diseases pose a significant threat to global agricultural production, often leading to substantial yield loss and major economic damage. Traditional disease detection methods rely on manual inspection, which is not only time-consuming and labo... read more
BACKGROUND: Pulmonary arterial hypertension (PAH) is a progressive vascular disease characterized by immune dysregulation and pulmonary vascular remodeling. This study aimed to identify immune-associated hub genes in PAH using an integrative bioinfor... read more
Advances in metagenomics, deep learning, and generative protein design have enabled broad in silico exploration of sequence space, but experimental characterization is still constrained by the cost and scalability of DNA synthesis. Here, we present O... read more
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