Studies in health technology and informatics
May 21, 2026
Accurate prediction of early functional outcome after acute ischemic stroke is critical for clinical decision-making. This retrospective cohort study developed and externally validated a machine learning model using routine clinical data from two set... read more
Studies in health technology and informatics
May 21, 2026
Regulators increasingly view real-world healthcare data and potential use of Artificial Intelligence (AI) approaches as vital for pharmacovigilance (PV). Large European and global initiatives have invested in the development of scalable pharmacovigil... read more
Studies in health technology and informatics
May 21, 2026
We applied explainable machine learning to optical coherence tomography (OCT) data from 168 pediatric NF-1 patients to predict vision abnormalities. The Balanced Random Forest model achieved an AUC-ROC of 0.82. SHapley Additive exPlanations (SHAP) an... read more
Studies in health technology and informatics
May 21, 2026
Using registry and questionnaire data from 47,235 chronic pain patients, we evaluated whether supervised learning outperforms clustering in predicting nine one-year outcomes. Supervised models showed small but consistent improvements (best RMSE 5.49 ... read more
Studies in health technology and informatics
May 21, 2026
Using the MIMIC-IV database (1,500-7,000 patients), we assess the robustness of healthcare machine learning models under controlled data quality (DQ) degradations applied to training or test data across five dimensions. Model performance declined wit... read more
Studies in health technology and informatics
May 21, 2026
The machine learning architecture DualNet was introduced for analysing both frontal and lateral X-rays of a patient for disease classification. Since the model lacks explainability methods, we extended the pytorch-grad-cam package for the application... read more
Studies in health technology and informatics
May 21, 2026
Automated analysis of histological sections in distraction osteogenesis can reduce manual effort and subjectivity in histological assessment. A 2D nnU-Net was trained to segment three characteristic tissue zones in sections of rat tibial distraction ... read more
Studies in health technology and informatics
May 21, 2026
Researching norovirus gastroenteritis retrospectively is challenging, since the absence of a disease record does not imply the absence of that disease. We compared three classification approaches in the UK Biobank: silver-standard labeled controls on... read more
Studies in health technology and informatics
May 21, 2026
Clinical guidelines are widely used in the medical practice. Temporal constraints-such as durations, intervals, and delays-are an intrinsic component of most guidelines. Existing approaches to computerized clinical guidelines (CIGs) typically include... read more
Studies in health technology and informatics
May 21, 2026
Cancer registry data is an important resource in cancer research, e.g. to formulate hypotheses for new interventions, to identify recruitment potentials for clinical trials or to evaluate side effects of new interventions on a large population, but r... read more
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