Inferring the biophysical parameters of conductance-based models (CBMs) from experimentally accessible recordings remains a central challenge in computational neuroscience. Spike times are the most widely available data, yet they reveal little about ... read more
Periodontitis is a chronic inflammatory disease driven by microbial dysbiosis, yet the microbial signatures associated with severity remain incompletely understood. This study investigated changes in subgingival microbial composition across clinicall... read more
The aviation system is safety-critical by nature, and any occurrence of an incident or accident can lead to the loss of human life and significant operational disruptions. The International Civil Aviation Organization (ICAO) emphasizes that every fli... read more
The Journal of bone and joint surgery. American volume
May 21, 2026
BACKGROUND: The use of large language models (LLMs) is increasingly common. However, LLMs may exhibit sycophancy, echoing users' beliefs while avoiding contradiction. In the present study, we describe sycophancy in general-purpose LLMs when applied t... read more
The role of active faults in driving rock uplift is well known, but their influence on rock damage and erosional efficiency remains unclear globally. Using 1744 beryllium-10 (10Be)-derived erosion rates, we show that erosional efficiency is elevated ... read more
Progress in the use of artificial intelligence (AI) to advance scientific discovery has made it increasingly realistic to envision automated "end-to-end science" (ETES) systems: integrated pipelines that could generate hypotheses, run experiments (in... read more
Annual review of genomics and human genetics
May 21, 2026
Noncoding variants occur within noncoding genes as well as within the regulatory nontranslated regions of protein-coding genes. It is important to be aware that these variants have been increasingly implicated in developmental disease through a varie... read more
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
May 21, 2026
Lung cancer remains the leading cause of cancer-related mortality worldwide despite advances in early detection and treatment. Furthermore, its epidemiology has undergone a profound transformation, necessitating a radical and comprehensive departure ... read more
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