Background: Heart failure (HF) is a major contributor to inpatient hospital utilization, with persistently high 30-day readmission rates. Existing prediction tools are frequently restricted to primary-diagnosis HF admissions, potentially excluding cl... read more
Background: Structuring oncology clinical notes into registry-grade variables is essential for research and care but remains labour-intensive and error-prone. Objective: To develop and evaluate a privacy-preserving large language model pipeline for o... read more
Background: Alzheimers disease (AD) is a multifactorial neurodegenerative disorder in which copper dyshomeostasis, mitochondrial stress, oxidative injury and immune dysregulation may contribute to pathogenesis. Cuproptosis, a copper-triggered regulat... read more
Background Patients worldwide receive healthcare in many languages, yet medical AI systems are validated almost exclusively in high-resource languages such as English and Chinese, exposing patients in other linguistic settings to unquantified diagnos... read more
The role of active faults in driving rock uplift is well known, but their influence on rock damage and erosional efficiency remains unclear globally. Using 1744 beryllium-10 (10Be)-derived erosion rates, we show that erosional efficiency is elevated ... read more
Progress in the use of artificial intelligence (AI) to advance scientific discovery has made it increasingly realistic to envision automated "end-to-end science" (ETES) systems: integrated pipelines that could generate hypotheses, run experiments (in... read more
Annual review of genomics and human genetics
May 21, 2026
Noncoding variants occur within noncoding genes as well as within the regulatory nontranslated regions of protein-coding genes. It is important to be aware that these variants have been increasingly implicated in developmental disease through a varie... read more
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
May 21, 2026
Lung cancer remains the leading cause of cancer-related mortality worldwide despite advances in early detection and treatment. Furthermore, its epidemiology has undergone a profound transformation, necessitating a radical and comprehensive departure ... read more
BACKGROUND: Mobile learning (mLearning) is widely used in medical education. Previous research has focused on technology acceptance and intervention effectiveness, but rarely on their integration. Using realist evaluation, this study investigated the... read more
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