Traditional drug discovery relies on rounds of screening millions of
candidate molecules with low success rates, making drug discovery time and
resource intensive. To overcome this screening bottleneck, we introduce
Latent-X, an all-atom protein de... read more
Journal of chemical information and modeling
Jul 25, 2025
Electrochemical promotion of catalysis (EPOC) provides an effective and versatile strategy to enhance catalytic activity, selectivity, and stability in the reverse water-gas shift (RWGS) reaction, facilitating efficient CO hydrogenation to syngas und... read more
Chemistry (Weinheim an der Bergstrasse, Germany)
Jul 25, 2025
Site-specific modification of protein termini, particularly the N-terminus, has emerged as a cornerstone of chemical biology and biotechnology, facilitating the engineering of therapeutic proteins and functional biomaterials. The N-terminus, with its... read more
Recent studies in speech-driven talking face generation achieve promising
results, but their reliance on fixed-driven speech limits further applications
(e.g., face-voice mismatch). Thus, we extend the task to a more challenging
setting: given a fa... read more
BACKGROUND: While codes suffice for identifying stroke events in surveillance, accurately classifying stroke types and subtypes using electronic health records remains challenging due to limitations in structured data. This often necessitates manual... read more
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences
Jul 25, 2025
BackgroundNon-contrast computed tomography (NCCT) is the first image for stroke assessment, but its sensitivity for detecting large vessel occlusion (LVO) is limited. Artificial intelligence (AI) algorithms may contribute to a faster LVO diagnosis us... read more
Drug-drug interactions (DDIs) arise when multiple drugs are administered
concurrently. Accurately predicting the specific mechanisms underlying DDIs
(named DDI events or DDIEs) is critical for the safe clinical use of drugs.
DDIEs are typically rep... read more
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