Background Patients worldwide receive healthcare in many languages, yet medical AI systems are validated almost exclusively in high-resource languages such as English and Chinese, exposing patients in other linguistic settings to unquantified diagnos... read more
Background: The clinical applicability of large language models (LLMs) in Parkinson's disease (PD) management remains insufficiently characterized, particularly in generative responses to clinical vignette scenarios. Objective: To evaluate the qualit... read more
Today, advancements in our understanding of cancer biology are increasingly attributed to large-scale clinical-molecular datasets. The case in point for multiple myeloma, the second-most prevalent haematological malignancy, is the CoMMpass study, a d... read more
Aims Active surveillance (AS) allows selected men with localized prostate cancer to defer curative therapy and reduce treatment morbidity. Conversion from AS to treatment is commonly triggered by Gleason grade group (GGG) upgrading on confirmatory bi... read more
Soft tissue sarcomas are a rare, heterogeneous group of tumors whose diagnosis remains challenging because of overlapping morphology and limited access to sarcoma-specialized pathologists. Although pathology foundation models have shown promise in co... read more
Background: Systematic literature reviews (SLRs) are essential in medical research, but are often time-consuming and costly, necessitating more efficient methods while maintaining accuracy. Objective: This study assessed the performance of a GPT-4o m... read more
Foundation models (FMs) are powerful tools to allow the broad clinical application of artificial intelligence (AI) in healthcare systems, offering adaptability to different disease, modalities and clinical settings. However, FMs require large-scale d... read more
Accurate risk stratification of pigmented skin lesions is critical for early melanoma detection and for reducing unnecessary excisions. Artificial intelligence (AI) is increasingly applied to dermoscopic image analysis, but its diagnostic performance... read more
Purpose: Modified Barium Swallow (MBS) studies utilize videofluoroscopy, a dynamic X-ray technique for evaluating swallowing anatomy and physiology. Each MBS exam typically includes multiple bolus trials, often involving different bolus consistencies... read more
Clonal haematopoiesis (CH) becomes ubiquitous as humans age. The role of somatic driver mutations in its development has been studied widely, but little is known about CH without identified genetic drivers, also known as "CH with unknown drivers" (CH... read more
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