BACKGROUND: Artificial intelligence (AI) augmentation of ECG assessment has significant potential to improve patient outcomes in acute coronary syndrome. read more
Clinical chemistry and laboratory medicine
Jul 25, 2025
OBJECTIVES: Use of machine learning (ML) in diagnostics offers promise to optimise interpretation of laboratory data and guide clinical decision-making. For this, ML-based outputs should provide robustly reproducible results at least as good as the u... read more
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Jul 25, 2025
PURPOSE: Intervertebral disc degeneration (IDD) is a major contributor to chronic low back pain. Magnetic resonance imaging (MRI) serves as the gold standard for IDD assessment, yet manual grading is often subjective and inconsistent. With advances i... read more
Traditional drug discovery relies on rounds of screening millions of
candidate molecules with low success rates, making drug discovery time and
resource intensive. To overcome this screening bottleneck, we introduce
Latent-X, an all-atom protein de... read more
Geriatrics & gerontology international
Jul 25, 2025
AIM: Multimorbidity and disability are prevalent in older adults, yet the relationship between specific multimorbidity patterns and disability is poorly understood. This study aimed to identify clinically significant multimorbidity patterns in older ... read more
Risk factor-based algorithms give a good estimate of cardiovascular (CV) risk at the population level but are often inaccurate at the individual level. Detecting preclinical atherosclerotic plaques in the carotid and common femoral arterial bifurcati... read more
BACKGROUND: While codes suffice for identifying stroke events in surveillance, accurately classifying stroke types and subtypes using electronic health records remains challenging due to limitations in structured data. This often necessitates manual... read more
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