Inherited genetic variation can weaken the ability of the immune system to detect and eliminate malignant cells, limiting the effectiveness of cancer immunotherapy. However, how germline polymorphisms shape the tumor immune microenvironment across ca... read more
Pancreatic ductal adenocarcinoma (PDAC) presents as a cancer with an especially poor prognosis, largely due to the challenges surrounding its early diagnosis. Liquid biopsy has emerged as a promising, noninvasive method for screening across a variety... read more
Decades of research aiming to develop effective smoking interventions have identified triggers that contribute to failed quitting attempts including environmental (e.g. location), social (presence of other smokers), or internal (e.g. stress). Here, i... read more
Urban heat islands (UHI) significantly elevate land surface temperatures (LST) in high-density subtropical cities like Osaka, Japan, exacerbating energy demand, health risks, and climate vulnerability. This study investigates LST drivers using freely... read more
Plant diseases are a serious danger to the world's food security, because they lower agricultural output and increase economic losses. Due to subjectivity, fluctuating lighting, and environmental unpredictability, traditional visual examination techn... read more
Dysphagia presents a serious risk of aspiration that requires continuous monitoring. This study introduces standardized 2 s voice segments for aspiration detection, derived from physiological constraints observed during clinical video-fluoroscopic sw... read more
Accurate prediction of global horizontal irradiance (GHI) is essential for optimizing solar energy utilization. Satellite-based datasets often overestimate GHI, leading to errors that hinder reliable solar resource assessment. This study presents a s... read more
Previous studies tracking the relationship between manipulations of C. elegans neurons and the resulting behavioral changes have called for the development of a connectome-constrained neural network model that describes the cascade from neurons to be... read more
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