Bone age assessment (BAA) is a widely used clinical technique that can accurately reflect an individual's growth and development level, as well as maturity. In recent years, although deep learning has advanced the field of bone age assessment, existi... read more
This article is based on the form of "VR + Art Platform" and designs an art management platform that integrates display, trading, and socializing. The development of front-end work is carried out using Unity 3D engine, and modeling software such as 3... read more
This study presents a machine learning framework for fracture risk prediction and in silico validation of synthetic biomedical data. A retrospective dataset comprising 169 patient records with clinically relevant variables, including age, sex, weight... read more
OBJECTIVE: This study evaluated whether radiomics analysis of standard hand radiographs could provide an automated and objective assessment of structural severity in hand osteoarthritis (HOA) compared to Kellgren-Lawrence (KL) scores, ranging from 0 ... read more
Determining the subcellular localization of proteins is critical for understanding their functional roles. With the rapid expansion of protein sequence databases, traditional experimental and homology-based approaches for Protein Subcellular Localiza... read more
The synthesis of key chiral intermediates via biocatalysis is of great importance in pharmaceutical manufacturing. In this study, we engineered a phenylacetone monooxygenase from Thermobifida fusca to enhance its catalytic activity for the synthesis ... read more
OBJECTIVE: To develop an interpretable ensemble machine-learning model to support risk stratification of elevated depression- and anxiety-related psychological distress in a large multistage survey sample of Chinese adults, and to examine nonlinear a... read more
Raspberry ketone synthase is the key enzyme for raspberry ketone biosynthesis, yet its activity and thermostability remain suboptimal for industrial use. By combining computational and deep-learning-guided design, we obtained a Rubus idaeus raspberry... read more
Genome editing has revolutionized molecular biology. It offers precise modification of genetic material across diverse organisms. This review outlines the evolution of genome editing technologies from homologous recombination to advanced Clustered Re... read more
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.