AI Medical Compendium

Artificial intelligence-guided engineering of a thermostable cellulase cocktail enables efficient biomass hydrolysis at elevated temperatures.

Bioresource technology Jul 17, 2026

Efficient lignocellulosic biomass conversion under industrially relevant high temperatures is limited by the thermolability of commercial cellulases and a lack of synergistic, system-level thermostable cocktails. To address this gap, a thermostable c... read more

From binary labels to dynamic landscapes: The evolving computational prediction of protein-RNA interactions through tasks and deep learning paradigms.

Biotechnology advances Jul 17, 2026

Protein-RNA interactions (RPIs) stand for the central process in post-transcriptional regulation and have catalyzed a fast proliferation of computational approaches in recent years. Adopting a task-oriented classification method, RPIs calculation pre... read more

Mapping Long-Term Soil Organic Carbon Stocks Across the Conterminous United States with Machine Learning.

Environmental research Jul 17, 2026

Soil organic carbon (SOC) is a critical component of the global carbon cycle, but existing estimates of SOC stocks across the contiguous United States (CONUS) vary widely for the top 30 cm, hindering efforts to assess carbon sequestration potential a... read more

Editorial Commentary: What Is the Future of Artificial Intelligence in Clinical Echocardiography?

Trends in cardiovascular medicine Jul 17, 2026

Multi-omics dissection of panicle development reveals a GSE9-centered regulatory network controlling rice grain shape.

Journal of advanced research Jul 17, 2026

INTRODUCTION: Rice panicle development is a key agronomic trait that critically determining grain yield and quality. However, the underlying molecular networks, particularly those regulated by de novo genes, remain inadequately characterized. OBJECTI... read more

Prospective Validation of Multi-week Inpatient Census Forecasting for Pediatric HSCT and Cellular Therapy.

Transplantation and cellular therapy Jul 17, 2026

BACKGROUND: Accurate inpatient census forecasting is important for cell therapy and blood and marrow transplantation (BMT) programs because bed capacity, staffing, and coordination of transplant care depend on anticipating occupancy several weeks in ... read more

Current Perspectives on Thyroid Nodule Evaluation: Integrating Cytomorphology, Ultrasound Risk Stratification, and Molecular Testing.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Jul 17, 2026

Fine-needle aspiration biopsy (FNAB) remains the cornerstone of preoperative evaluation of thyroid nodules and represents one of the most enduring and successful applications of cytopathology in clinical medicine. Over the past decade, however, the r... read more

Therapeutic potential of pachymic acid in glioma: a comprehensive approach combining experimental validation, network pharmacology, and machine learning.

Brain research Jul 17, 2026

Pachymic acid (PA) is a natural active component of Poria cocos(Schw.)Wol. Although PA exhibits antitumor activity in multiple cancers, its effects and mechanisms against glioma remain elusive. This study aimed to investigate the anti-glioma effects ... read more

PAN4, an AI-designed host-directed immunomodulatory peptide, promotes PGRP-SC1a-associated intestinal immune homeostasis in Drosophila melanogaster.

Insect biochemistry and molecular biology Jul 17, 2026

We identify PAN4 (GAYTFKIRRK), an AI-designed host-directed immunomodulatory peptide, as a modulator of intestinal immune homeostasis in Drosophila melanogaster. PAN4 lacks detectable bactericidal activity against Pseudomonas aeruginosa in vitro but ... read more

Preliminary Analysis of Biomarkers and Molecular Mechanisms in Graves' ophthalmopathy Patients Related to the Retinol Metabolic Pathway.

Experimental eye research Jul 17, 2026

OBJECTIVE: This study aimed to identify potential biomarkers for Graves' ophthalmopathy (GO) through bioinformatics analyses and to validate their expression at the cellular level, thereby providing new therapeutic targets for GO. METHOD: Differentia... read more

Artificial Intelligence Medical Compendium