Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
May 20, 2026
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with limited therapeutic options. Polybrominated diphenyl ethers (PBDEs) are persistent environmental pollutants, yet whether the dominant human congener, 2,2',4,4',5,5'-h... read more
OBJECTIVE: To develop and comparatively evaluate multiple deep learning architectures for automated detection and grading of oral epithelial dysplasia in hematoxylin and eosin (H&E)-stained histopathological images. METHODS: A total of 2,080 digitize... read more
The increasing prevalence of chronic diseases related to suboptimal diet quality in the US and worldwide contributes to burgeoning healthcare costs and excess death and disability. Changing dietary intake is essential but difficult because dietary be... read more
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
May 20, 2026
Post-printing drying conditions could affect the quality of oral use printlets elaborated by semi-solid extrusion (SSE) 3D printing, yet their systematic characterization as Critical Process Parameters (CPPs) remains limited. This study evaluated the... read more
Steroidal alkaloids are a structurally diverse class of nitrogen-containing natural products with strong pharmacological potential, including anticancer, anti-inflammatory, and neuroprotective activities. Despite their therapeutic potential, clinical... read more
Journal of thrombosis and haemostasis : JTH
May 20, 2026
BACKGROUND: Idiopathic venous thromboembolism (VTE) occurs in the absence of provoking factors, limiting the efficacy of current risk stratification. In parallel, the lack of integration between transcriptomic data and established risk factors preven... read more
Central line-associated bloodstream infection (CLABSI) is a frequent and severe complication in children undergoing treatment for acute leukemia, substantially compromising therapeutic outcomes. This study aimed to develop a machine learning-based pr... read more
The rapid integration of artificial intelligence (AI) and machine learning into predictive toxicology has transformed chemical hazard identification, toxicity endpoint forecasting, and risk assessment for pharmaceuticals, environmental pollutants, an... read more
BACKGROUND: T-2 toxin is a highly toxic mycotoxin commonly present in food and the environment, with accumulating evidence supporting its hepatotoxic potential. However, the molecular events linking T-2 toxin exposure to liver fibrosis remain insuffi... read more
BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by active angiogenesis and heterogeneous vascular patterns. However, vascular pattern profiling in tumors and its clinical significance remain unexplored. OBJECTIVES: This study aimed to dev... read more
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