Purpose: Modified Barium Swallow (MBS) studies utilize videofluoroscopy, a dynamic X-ray technique for evaluating swallowing anatomy and physiology. Each MBS exam typically includes multiple bolus trials, often involving different bolus consistencies... read more
Clonal haematopoiesis (CH) becomes ubiquitous as humans age. The role of somatic driver mutations in its development has been studied widely, but little is known about CH without identified genetic drivers, also known as "CH with unknown drivers" (CH... read more
Large language models (LLMs) are increasingly used for lay health queries, yet may abandon correct recommendations under pressure, a vulnerability termed sycophancy. We evaluated sycophancy across five frontier LLMs (Claude Opus 4.6, Claude Sonnet 4.... read more
Importance. Large language models are increasingly explored as clinical decision support tools in orthodontics, yet existing evaluations have been confined to knowledge based question answering where reported accuracy ranges from 18% to 100%. No stud... read more
Purpose: Genetic risk scores (GRSs) are summaries of genetic data that can improve prediction of disease risk and progression. GRSs are increasing available but rely on high quality input data to produce good output results; with noisy or missing inp... read more
Background Delineating the cellular origins of extracellular vesicles (EVs) enables the detection of clinically relevant changes in dynamic and complex tissues, such as the endometrium, which are not characterizable through single biomarker assays. T... read more
Background: Aberrations in neuro-immune, metabolic, and oxidative stress (NIMETOX) pathways are implicated in major depressive disorder (MDD). First-episode simple dysmood disorder (FE-SDMD) without metabolic syndrome offers a unique model to investi... read more
Background: Heterogeneity in symptom presentation and treatment response in irritable bowel syndrome (IBS) remains poorly understood. The gut microbiota may contribute to this variability, but its role in shaping symptom trajectories and responses to... read more
Leishmaniasis, a climate-sensitive zoonotic neglected tropical disease, is transmitted by Phlebotomine sand flies and closely linked to socio-economic inequities. Understanding its spatio-temporal dynamics under environmental and social change is cri... read more
The gene signatures of Alzheimer's Disease (AD) brains reflect an output of a complex interplay of genetic, epigenetic, epi-transcriptomic, and post-transcriptional regulation., yet the dominant factor shaping these signatures remains unclear. To ide... read more
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.