Context-dependent alternative splicing plays a critical role in disease pathogenesis and organ development, but its complex regulation remains challenging to predict. Here, to address this, we developed HELIX, a hierarchical deep learning framework t... read more
Deep convolutional neural networks (DCNNs) achieve high object classification performance; however, how representational preferences systematically evolve across hierarchical layers remains unclear. Although previous studies using stylized images hav... read more
Wave equations with nonlocal conditions appear in many scientific and engineering applications, such as, the population dynamics, the mathematical biology, and the materials science. The numerical challenge mainly stems from nonlocal terms, whose glo... read more
Classification of brain tumors is a difficult problem in medical imaging analysis. Over the past few years, various deep learning-based techniques have been employed for detecting and classifying tumors from Computed Tomography (CT) and Magnetic Reso... read more
Reservoir computers, using recurrent neural networks with fixed random connections, are known to perform a wide range of information-processing tasks. Yet the transformations taking place within the reservoir, the interaction between input matrix, re... read more
The classification of immunophenotypes in muscle-invasive bladder cancer (MIBC) is critical for predicting immunotherapy response and clinical outcomes, yet current assessment methods lack standardization and scalability. We developed and validated a... read more
BACKGROUND: Lymph node metastasis (LNM) is an important prognostic factor but is often underdiagnosed due to limitations in conventional assessment methods. We aimed to develop a deep learning (DL) model to predict LNM status from primary gastric can... read more
Food microbiology education faces significant challenges including prohibitive costs, safety concerns, and limited accessibility, as traditional laboratory-based instruction requires expensive infrastructure, specialized equipment, and stringent bios... read more
Early and accurate diagnosis of breast cancer is critical for minimizing needle biopsies and enhancing patient outcomes and requires effective integration of multimodal information. In this article, we introduce a breast cancer intelligent non-invasi... read more
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