OBJECTIVES: To examine the relationship between cardiorespiratory fitness (CRF) and brain aging, and the extent to which this is mediated by systemic inflammation. METHODS: This study included 4,770 adults from the UK Biobank (mean age: 55.37 ± 7.50 ... read more
A deep understanding of chromatin interactions is crucial for elucidating the mechanisms of gene expression regulation. Although various computational methods have been proposed to predict chromatin interactions and address the limitations and high c... read more
Early detection of tumors constitutes a cornerstone of cancer prevention and control. Medical assessments alongside emerging screening modalities provide a foundational framework that facilitates early detection and contributes to reductions in both ... read more
OBJECTIVE: To develop and validate dynamic machine-learning models to predict 6-month adverse outcomes in intermittent claudication (IC), enabling risk-ranked prioritization for surveillance and timely revascularisation. METHODS: This study included ... read more
Clinica chimica acta; international journal of clinical chemistry
May 19, 2026
Lung cancer remains the leading cause of cancer-related mortality worldwide, with early detection being critical for improving survival outcomes. Liquid biopsy using circulating biomarkers from blood, urine, saliva, sputum, exhaled breath condensate ... read more
INTRODUCTION: Community-acquired pneumonia (CAP) is one of the leading causes of death globally. Changing antibiotic resistance profiles, paucity of reliable CAP mortality prediction models, and ageing populations will increase its burden. This study... read more
Chemical tools capable of effectively phenotyping drug-resistant bacteria can help improve therapeutic efficacy toward bacterial infections. While conventional techniques rely on labor-intensive procedures for the determination of bacterial susceptib... read more
Ultrasound is widely used in breast cancer diagnosis due to its cost-effectiveness, non-invasiveness, and radiation-free properties. Computer-aided diagnostic systems based on dynamic breast ultrasound videos have advanced rapidly. However, existing ... read more
Journal of environmental health science & engineering
May 19, 2026
Polycyclic aromatic hydrocarbons (PAHs) pose serious risks to soil and human health, necessitating effective remediation strategies. This study investigates the efficiency of hybrid ultrasonication-ozonation treatment for the removal of Anthracene (A... read more
Organic aerosol (OA) constitutes a major fraction of atmospheric fine particulate matter, yet quantifying its sources and transformation pathways remains a significant scientific challenge. To address this, field measurements were conducted in Januar... read more
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