AI Medical Compendium

Artificial Intelligence-Generated Synthetic Data in Healthcare: A False Promise for Underserved Populations?

Bioethics May 19, 2026

Artificial intelligence (AI)-generated synthetic data has emerged as a promising solution to address the underrepresentation of underserved populations in medical AI systems. By artificially generating data that mimics real-world patient information,... read more

Comprehensive Review of Contrastive and Generative Self-Supervised Learning for Small Molecular Representation.

Journal of chemical information and modeling May 19, 2026

Drug discovery is a complex and resource-intensive process, where developing effective computational tools to analyze vast and heterogeneous molecular data is paramount. In this landscape, contrastive and generative learning have emerged as two found... read more

Spatially Sussing Out the TME, No Tissue Needed.

Cancer discovery May 19, 2026

Through machine learning, researchers have uncovered distinct spatial ecotypes in the tumor microenvironment that are broadly conserved across multiple cancers and may correlate with response to immune checkpoint blockade. These ecotypes are also ide... read more

Advanced High-Entropy Biomaterials (HEBs).

Small (Weinheim an der Bergstrasse, Germany) May 19, 2026

High-entropy materials (HEMs), characterized by their unique multi-principal elemental compositions (typically five or more elements in near-equiatomic mixing), represent a paradigm-shifting class of substances. This compositional hallmark leads to f... read more

Unraveling the Multifunctional and Translational Paradigm of Nanoparticulate Systems against Colorectal Cancer.

ACS applied bio materials May 19, 2026

Colorectal cancer (CRC) is a health burden due to its high mortality rate, recurrence rate, and drug resistance. The limitations of traditional methodologies (such as radiotherapy, chemotherapy, surgery, and targeted active ingredients) include ineff... read more

Response to letter regarding "artificial intelligence-assisted real-time nasopharyngeal cancer diagnostic model enhances rhinologist performance: a prospective multi-reader study".

Annals of medicine May 19, 2026

Novel biomarkers driving treatment selection in metastatic castration-sensitive prostate cancer: fundamentals of personalized clinical decision making.

Expert review of clinical pharmacology May 19, 2026

INTRODUCTION: Prostate cancer is well known to be androgen-dependent, with growth directly relying on the androgen receptor signaling pathway. In fact, androgen deprivation therapy, with or without Docetaxel and/or newer hormonal drugs such as Abirat... read more

Nanothermodynamics of Hydrogenated Diamond Clusters: Size-Dependent Transition Pressures and Stability.

The journal of physical chemistry letters May 19, 2026

Nanodiamonds hold promise for quantum sensing, tribology, and biomedicine, but their controlled synthesis at atmospheric pressure remains limited due to poor understanding of how surface chemistry governs nanoscale sp3 carbon stability. Hydrogen adso... read more

A Review on Single-Atom Catalysts-Based Gas Sensors from Functional Design to Mechanism Elucidation.

ACS applied materials & interfaces May 19, 2026

Single-atom catalysts (SACs) perform a pivotal role in gas sensing due to their maximized atomic utilization and unique physicochemical properties, effectively overcoming the limitations of traditional sensors in sensitivity, selectivity, and respons... read more

Rapid Cas13a-based penA genotyping for cefixime susceptibility in Neisseria gonorrhoeae.

mSphere May 19, 2026

UNLABELLED: Antimicrobial resistance in Neisseria gonorrhoeae is an urgent public health threat. Resistance-guided therapy can assure appropriate treatment and reintroduce alternative therapeutic options by identifying genetic predictors of resistanc... read more

Artificial Intelligence Medical Compendium