AI Medical Compendium

Leveraging Chemical Hidden-Space Representations Effectively in Bayesian Optimization for Experiment Design through Dimension-Aware Hyperpriors.

Journal of chemical theory and computation May 15, 2026

Hidden-space molecular representations derived from pretrained graph neural networks, transformer models, and large language models offer an appealing alternative to conventional encodings for Bayesian optimization (BO) in chemical experiment design.... read more

Remission, Relapse, and Thyroid-Related Parameters Measurement at Discontinuation of Low-Dose Anti-Thyroid Drugs in Graves' Disease.

Endocrinology and metabolism (Seoul, Korea) May 15, 2026

BACKGROUND: This study aimed to elucidate the relationship between thyroid-related parameters and the prognosis of Graves' disease (GD). METHODS: This retrospective cohort study included patients newly diagnosed with GD between January 2009 and Decem... read more

Thiazolyl Blue as a High-Efficiency Leveler for Conformal Copper Electrodeposition in High-Aspect-Ratio PCB Through-Holes.

Langmuir : the ACS journal of surfaces and colloids May 15, 2026

Driven by the rapid development of 5G/6G communications, high-performance computing, and artificial intelligence, the metallization of high-aspect-ratio through-holes (THs) in printed circuit boards (PCBs) imposes stringent requirements on the thickn... read more

PythiaStudio: a one-stop protein engineering platform powered by Pythia model suite.

Nucleic acids research May 15, 2026

Predicting how mutations affect protein stability and protein-protein binding affinity is crucial for protein engineering and drug development. Although several computational tools have been developed for these tasks, they often require specialized e... read more

Diffusion-Based Generative Model With Scaffold-Hopping Strategy Yields Highly Potent Bioactive Molecules.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) May 15, 2026

As a critical step in drug discovery, lead optimization is a profoundly complex endeavor with a notoriously high failure rate, as it necessitates the simultaneous optimization of multiple, often conflicting parameters, including physicochemical prope... read more

Gradient Electrode-Electrolyte Interface Enables Ultrastable Piezoionic Sensor for Artificial Intelligence.

Small (Weinheim an der Bergstrasse, Germany) May 15, 2026

Piezoionic sensors perceive the physical world based on polymer ionogels with advantages of flexibility, lightweight, and high sensitivity, and are suitable for physical signal extraction and virtual space construction in artificial intelligence. How... read more

PlasticAnalytics: A Deep Learning-Powered Spectral Library and Analytical Suite.

Environmental science & technology May 15, 2026

PlasticAnalytics provides an automated workflow that addresses key bottlenecks in vibrational spectroscopic analysis of microplastics by Raman spectroscopy and Fourier transform infrared spectroscopy (FTIR). The preprocessing framework integrates an ... read more

Smartphone-Based Pupillometry for Noninvasive Detection of Elevated Intracranial Pressure in Nepali Acute Brain Injury Patients: A Pilot Study.

Journal of neurosurgical anesthesiology May 15, 2026

BACKGROUND: Intracranial hypertension is a life-threatening complication of acute brain injuries such as traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), or intracerebral hemorrhage (ICH). In low-income and middle-income countries (LMICs)... read more

Artificial Intelligence-Based Perioperative Assessment for Elderly Patients Undergoing Inguinal Hernia Repair in a Resource-Limited Setting.

World journal of surgery May 15, 2026

Unveiling the gap in heart failure: a Brazilian Unified Health System study.

Journal of global health May 15, 2026

BACKGROUND: Heart failure (HF) decompensation is the leading cause of hospitalisations in developed countries and the third most common cause in Brazil. Underdiagnosis or misdiagnosis thereof remains a critical challenge and with significant implicat... read more

Artificial Intelligence Medical Compendium