American journal of pharmaceutical education
May 15, 2026
OBJECTIVE: To investigate the accuracy and reliability of AI chatbots to estimate pharmacokinetic parameters from limited patient samples and population data for potential application in teaching Bayesian concepts. METHODS: Two plasma concentration-t... read more
While cell shape fundamentally governs tissue function, the underlying links between single-cell shape and protein expression have been difficult to resolve due to limitations in imaging multiplexing and population averaging. Here, we use multiplexed... read more
Inflammatory breast cancer (IBC) is a rare yet highly aggressive subtype of breast cancer, characterized by distinct clinical features, rapid progression, and complex biology. Despite decades of research, patient outcomes remain poor, underscoring th... read more
Journal of Korean Neurosurgical Society
May 15, 2026
Pediatric neurosurgery increasingly utilizes precision medicine, but practitioners encounter challenges in translating complex data into individualized care. Digital twin (DT) bridges this gap by linking real-world data to a dynamic patient in-silico... read more
MOTIVATION: Analysis of single cell ATAC-seq and RNA-seq data has allowed to gain unprecedented insights into gene regulation by allowing to define cell type-specific regulatory regions and their effects on gene expression. While powerful, such analy... read more
Interdisciplinary cardiovascular and thoracic surgery
May 15, 2026
OBJECTIVES: Subclinical leaflet thrombosis is an early form of bioprosthetic valve dysfunction after transcatheter aortic valve implantation. Predicting subclinical leaflet thrombosis remains challenging. We aimed to apply machine learning not only t... read more
Social cognitive and affective neuroscience
May 15, 2026
Humans rapidly detect and interpret sensory signals that have emotional meaning. The posterior superior temporal sulcus (pSTS) and amygdala are known to be critical for this ability, but their precise contributions remain contentious. Here we investi... read more
This study developed a web-based online monitoring system for assessing the freshness of stewed beef by integrating an intelligent colorimetric film with deep learning. A pH-responsive colorimetric film was fabricated using mulberry anthocyanin extra... read more
Glaucoma is a leading cause of irreversible yet preventable blindness in working-age populations. Clinical diagnos is currently relies on functional visual field (VF) examinations to evaluate visual function and monitor disease progression, but these... read more
PURPOSE: We aimed to develop a generalizable machine learning model that leverages electronic medical record (EMR) data to predict candidemia using information available on or before the date of blood culture collection. METHODS: This study included ... read more
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