Population-based diabetic retinopathy (DR) screening requires diagnostic strategies that optimize clinical utility by balancing missed disease against referral burden. We performed a Preferred Reporting Items for Systematic Reviews and Meta-Analyses ... read more
PURPOSE: Osteoarthritis (OA) is now understood as a heterogeneous syndrome driven by diverse biological, biomechanical, metabolic, genetic, and molecular mechanisms. This variability explains differences in disease progression and treatment response,... read more
INTRODUCTION: Artificial intelligence (AI) for surgical workflow analysis often fails to generalize because surgical actions lack a standardized, fine-grained representation. Gesture-level "tokenization" of surgery, capturing instrument-tissue intera... read more
BACKGROUND: Artificial intelligence (AI), augmented reality (AR), and robotics are rapidly transforming aesthetic practice. Despite their growing integration, evidence on their clinical applications, performance, and challenges in cosmetic procedures... read more
BACKGROUND: Pediatric heart failure (PHF) carries a high mortality burden, yet the prognostic value of admission blood pressure (BP) remains poorly defined, and evidence-based thresholds for risk stratification are lacking. METHODS: This retrospectiv... read more
UNLABELLED: Immunization is one of the most effective interventions to prevent infectious diseases. Identifying individuals at risk of non-adherence to immunization schedules could enable early interventions to improve coverage. With the increasing a... read more
INTRODUCTION: The multidisciplinary heart team (HT) remains the cornerstone of decision-making for complex cardiovascular disease. Large language models (LLMs) and other generative artificial intelligence models have recently emerged as potential dec... read more
OBJECTIVES: To develop and validate interpretable machine learning (ML) models incorporating MRI-derived paraspinal muscle parameters to predict new vertebral compression fractures (NVCF) after vertebral augmentation. MATERIALS AND METHODS: This mult... read more
Although many predictive models for metabolic dysfunction-associated steatotic liver disease (MASLD) have been developed, their performance remains suboptimal. We aimed to develop an interpretable machine learning (ML)-based plasma biomarker model fo... read more
Whole-slide histopathological images (WSIs) constitute a fundamental approach in disease diagnosis and prognosis. Recently emerging spatial transcriptomics (ST) methods can reveal the spatial gene expression landscape behind the histopathological ima... read more
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