OBJECTIVES: Depth of stromal invasion (DSI) is a key prognostic factor significantly influencing treatment decisions in early-stage cervical cancer (ESCC). This study aims to develop an explainable multimodal data fusion model integrating MRI, radiol... read more
INTRODUCTION: Nemolizumab is a humanized monoclonal antibody that specifically inhibits the receptor for interleukin-31, the major pruritogen in atopic dermatitis (AD). While the patient profile associated with the early therapeutic response to nemol... read more
Omics : a journal of integrative biology
May 15, 2026
Metabolomics is the comprehensive analysis of small-molecule metabolites in living systems and is increasingly being applied in forensic science and health diagnostics. This review broadly integrates the foundational principles of metabolomics, key a... read more
Artificial olfactory systems represent biomimetic platforms that emulate biological olfaction for volatile compound detection and discrimination. Biological olfaction achieves efficient perception through the specific binding of volatile molecules to... read more
The integration of artificial intelligence (AI) into second and foreign language (L2) education has increased significantly; however, its emotional impact on teachers remains underexplored, particularly in less commonly taught languages (LCTL) such a... read more
BMC medical informatics and decision making
May 15, 2026
BACKGROUND: Sleep apnea syndrome (SAS) is closely related to an increased risk of non-alcoholic fatty liver disease (NAFLD), but current clinical tools lack the integration of multidimensional data for accurate risk prediction. This study employs var... read more
BACKGROUND: Acute lung injury and its severe form, acute respiratory distress syndrome (ARDS), represent life-threatening conditions with high mortality rates. Since the lung is the primary target organ in systemic inflammatory conditions like sepsis... read more
BACKGROUND: Survival analysis in high-dimensional (HD) and multi-block (MB) settings, such as omic and multi-omic studies, poses major methodological challenges due to multicollinearity, low events-per-variable ratios, and limited model interpretabil... read more
In drug discovery, nuisance compounds are chemicals that interfere with biochemical or cell-based assays, often generating misleading signals unrelated to true activity. These molecules operate through diverse, context-dependent mechanisms, ranging f... read more
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