The mutation accumulation (MA) hypothesis posits that somatic mutations progressively escape selection and degrade tissue function during aging. Direct tests of this idea have been limited by the difficulty of predicting, at scale, the molecular cons... read more
European journal of preventive cardiology
May 15, 2026
AIMS: Hyponatraemia is a potential serious adverse drug reaction to treatment with thiazide diuretics. This study aimed to determine whether individuals at high risk of developing thiazide-induced hyponatraemia can be identified before treatment init... read more
BACKGROUND AND AIMS: Paediatric myocardial strain analysis through echocardiography is often characterized by high variance and limited precision, highlighting the need for a standardized and vendor-agnostic approach applicable for diverse image qual... read more
BACKGROUND AND AIMS: Identification of patients with acute coronary syndrome requiring coronary revascularization can be challenging due to inconclusive electrocardiogram (ECG) findings or biomarker results. A deep learning model to detect ECG patter... read more
Despite their high energy density, layered cathode materials suffer from instability in aqueous lithium-ion batteries. LiCoO2, as a prototypical layered oxide cathode, exhibits a pronounced dependence of aqueous stability on oxygen stacking, with mar... read more
The precise manipulation of photochemical reactions across broad configurational spaces requires sophisticated design of external control fields. Using the photoisomerization of a molecular motor as a prototype, this study integrates enhanced samplin... read more
Chemphyschem : a European journal of chemical physics and physical chemistry
May 14, 2026
Machine-learning potentials (MLPs) extend the time and length scales of atomistic simulations, enabling the study of complex systems, such as electrolyte solutions. Yet most models face a tradeoff between accuracy, computational cost, and the ability... read more
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
May 14, 2026
PURPOSE: To evaluate the performance of a Transformer-based U-Net, TransDisCo, for distortion correction in clinical diffusion-weighted imaging (DWI), including high b-value DWI, diffusion tensor imaging (DTI), and diffusion kurtosis imaging (DKI) an... read more
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
May 14, 2026
PURPOSE: This study evaluated salivary gland function using MR cine sialography (MRCS) based on the time-spatial labeling inversion pulse (Time-SLIP) technique combined with a deep learning reconstruction-based denoising method (dDLR). Bilateral sali... read more
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