Artificial intelligence (AI)-enabled systems must simultaneously improve the Quintuple Aim and digital health maturity, including equitable access to and quality and interoperability of data, tools, agents, and services. This requires a comprehensive... read more
Osteoporosis often lacks accessible screening tools, leading to underdiagnosis and increased fracture risk. We explored the potential of a retinal aging biomarker, measured by the RetiAGE algorithm, in stratifying osteoporosis risk. Cross-sectional a... read more
With geotechnical engineering facing more complex environmental challenges, accurately predicting the mechanical behavior of rocks under dynamic loading becomes essential for maintaining structural safety. In this study, the dynamic compressive stren... read more
BACKGROUND: Clinical notes are the most abundant data type within electronic health records; however, their highly unstructured format presents significant challenges for supervised natural language processing (NLP) methods. The NLP community is incr... read more
Journal of the American Medical Informatics Association : JAMIA
May 14, 2026
OBJECTIVES: Prediction models are increasingly used in healthcare for risk stratification and personalized care. Many models are developed using machine learning, which requires tuning hyperparameters to maximize performance based on a chosen loss fu... read more
This study examines inter-city heterogeneity in China's high-tech industries from a regional innovation systems (RIS) perspective, with a particular focus on how variations in knowledge production, technological application, and actor configurations ... read more
Oasis farmlands are the core grain production carrier in arid regions, where soil heavy metal contamination directly threatens regional agricultural product safety and resident health. This study developed an integrated framework of stratified spatia... read more
BACKGROUND: The impact of estimated pulse wave velocity (ePWV) on the prognosis of cardiovascular-kidney-metabolic (CKM) syndrome has not been explored. This study investigated the association between ePWV and mortality and its predictive performance... read more
BACKGROUND: The pathogenic mechanisms underlying rheumatoid arthritis (RA) remain elusive. Lactylation, a novel post-translational modification, may regulate immune and metabolic reprogramming, underscoring the imperative to delineate lactylation-rel... read more
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