AIMS: To investigate the changes in choroidal optical coherence tomography (OCT) radiomic features, their correlations with visual acuity and utility in identifying pathological myopia (PM). METHODS: A total of 288 myopic participants aged 18-50 year... read more
Plant cell walls are complex networks of polysaccharides that underpin plant structure and provide dietary fibers that promote human health. These polymers are assembled and remodeled by carbohydrate-active enzymes (CAZymes), which have been more cha... read more
This study introduces a probabilistic framework for patient-specific quality assurance (PSQA) in volumetric modulated arc therapy (VMAT), using gamma pass rates obtained from both measurement-based and independent calculation-based PSQA. The model qu... read more
Prediction of chemical compounds' toxicity enables efficient and rapid screening at the cost of utilizing experimental data as a foundation for artificial intelligence (AI) models. Given the constraints of limited data availability, few-shot learning... read more
Wearable technologies have the potential to transform ambulatory and at-home hemodynamic monitoring by providing continuous assessments of cardiovascular health metrics and guiding clinical management. However, existing cuffless wearable devices for ... read more
Sequence-based deep learning has advanced genome interpretation, yet most models remain task-specific and rely on retraining, limiting scalability across biological contexts. Here we present SUCCEED, a supervised multi-task DNA foundation model pretr... read more
Fluoride contamination in coastal aquifers is difficult to evaluate because its mobilisation is controlled by overlapping and seasonally dynamic non-stationary hydrogeochemical processes influenced by seawater intrusion, lithological heterogeneity, r... read more
The ever-growing demand of soft strain sensors in ubiquitous electronics poses urgent need of device durability innovations to reduce resource waste. As most soft sensors use non-degradable materials, it is important to ensure durable sensor performa... read more
​Soil microbiota is central to agroecosystem sustainability, influencing fertility, plant health, and resilience. Agricultural practices shape these communities in distinct ways: conventional systems, with intensive chemical inputs, often promote mic... read more
Organoids offer a powerful platform to model human development and disease in vitro, while preserving key features of in vivo tissue architecture and complexity. In this study, we developed a protocol to generate human induced pluripotent stem cell (... read more
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