BACKGROUND: Diabetic foot ulcers (DFUs) represent a severe chronic complication of diabetes and are characterized by persistent impairment of wound healing, accompanied by defective angiogenesis, chronic inflammation, and dysregulated extracellular m... read more
Computational Pathology is a novel discipline at the intersection of pathology and computer science, driven by the recent advances in machine learning and image analysis. Nevertheless, combining the insights from both disciplines remains challenging,... read more
Acute kidney injury (AKI) is common in the intensive care unit (ICU), and fixed creatinine thresholds may miss clinically relevant dynamics. We tested whether a deep-learning anomaly signal from short creatinine-estimated glomerular filtration rate (... read more
This study provides a comprehensive evaluation and classification of 35 soft decision-making (SDM) algorithms based on fuzzy parameterized fuzzy soft matrices (fpfs-matrices). Although fpfs-matrices offer a strong mathematical framework for modeling ... read more
Langmuir : the ACS journal of surfaces and colloids
May 13, 2026
The replicative senescence during in vitro expansion severely limits the clinical application of human umbilical cord mesenchymal stem cells (hUC-MSCs). Existing senescence assessment methods still face significant limitations in terms of noninvasive... read more
Proceedings of the National Academy of Sciences of the United States of America
May 13, 2026
Many strategic decisions involve both substantial complexity and time pressure, but the association between decision speed and decision quality of cognitively demanding strategic decisions is not well understood. This paper presents evidence on this ... read more
Proceedings of the National Academy of Sciences of the United States of America
May 13, 2026
Multiscale systems are ubiquitous in science and technology, but are notoriously challenging to simulate as short spatiotemporal scales must be appropriately linked to emergent bulk physics. When expensive high-dimensional dynamical systems are coars... read more
SpliceAI is the leading tool for predicting splice-altering variants, but restrictive licensing limits clinical adoption. While open-source implementations have been published with author-reported comparisons, independent benchmarking across diverse ... read more
Accurate, continuous monitoring of psychophysiological states is central to understanding stress and autonomic dysfunction across diverse medical contexts. Current approaches such as polygraphy and polysomnography rely on cumbersome, wired sensors th... read more
Autonomous microrobots can reach hard-to-access regions in the human body for minimally invasive therapy. However, their microscale size limits the integration of on-board memory, making their operation dependent on external controls. Here, we develo... read more
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