Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 20,341 to 20,350 of 215,962 articles

A CBF-SA module links wound-induced evaporative cooling to tissue repair in plants

bioRxiv
Repairing damaged tissues is essential for the survival of all organisms. In plants, tissue injury rapidly triggers defense and repair programs. However, the molecular mechanisms linking early injury cue to the later stages of wound repair remain unc... read more 

Transferable Transcriptional Topic Modeling Traces Medulloblastoma Subtypes to Distinct Cerebellar Developmental States

bioRxiv
Single-cell transcriptomics transformed our understanding of cellular heterogeneity, yet cross-dataset comparison remains fundamentally limited by batch effects, technology differences, and inconsistent annotation frameworks. These challenges have im... read more 

Cadence: A Benchmark Evaluation of the Narrative Velocity Framework for Next Clinical Event Prediction in MIMIC-IV

bioRxiv
Objective: How structured clinical features and cluster-semantic embeddings interact under self-distillation in EHR prediction models is unknown. Existing approaches treat these sources separately (gradient-boosted trees exploit tabular features whil... read more 

Learning activator-inhibitor dynamics at the cell cortex with neural likelihood ratio estimation

bioRxiv
A key question in cell biology is how cell-scale organization emerges from a given set of molecular players and rules of interaction. Given its multiscale nature, addressing this question requires a combination of experimental perturbation, mathemati... read more 

BioMADE: Predicting Torsades de Pointes from molecular structures through biologically informed representations

bioRxiv
Drug-induced arrhythmias, particularly Torsades de Pointes (TdP), pose a significant risk to patient safety and can sometimes have life-threatening outcomes. They remain a major concern in drug development and regulation. Machine learning (ML) has be... read more 

Talk2QSP: Deriving Executable Scenarios from Unstructured Literature via Human-in-the-Loop Agents

bioRxiv
Quantitative Systems Pharmacology (QSP) models play an inherently interventional role in pharmaceutical research and development, functioning as executable causal systems for designing, evaluating, and replacing clinical trials. However, deploying QS... read more 

FiberLM: A Transformer-Based Model for Mouse Brain Diffusion MRI Tractography Guided by Viral Tracer Data

bioRxiv
Diffusion MRI (dMRI) tractography provides a non-invasive method for mapping whole-brain structural connectivity. However, its application is limited by substantial false-positive and false-negative connections. While deep learning based methods have... read more 

3DBrainOne: an integrated end-to-end platform for 3D histological analysis of whole mouse brains

bioRxiv
Three-dimensional (3D) whole-organ imaging and analysis at cellular resolution (termed 3D histology) provide profound insights into the organization and interactions of cells throughout organs. However, the quantitative analysis of these massive data... read more 

Predicting Discrete Structural Transformations in Small Molecules from Tandem Mass Spectrometry

bioRxiv
Tandem mass spectrometry (MS/MS) fragments molecules into smaller pieces, generating spectra composed of m/z values and intensities that encode structural information for molecular annotation. With increasing mass spectrometry data acquisition speeds... read more 

sxRaep: A Rapid and Accurate Enzyme Predictor for high-throughput mining of enzymatic sequences

bioRxiv
Metagenomic sequencing generates petabyte-scale sequence datasets that strain both deep learning and alignment based enzyme annotation tools. A lightweight rapid and accurate filter tool is needed to identify enzymatic sequences prior to resource-int... read more