Flat urothelial lesions represent a diagnostically challenging and clinically significant spectrum in bladder pathology. Distinguishing urothelial carcinoma in situ (CIS) from precursor lesions such as dysplasia remains problematic due to overlapping... read more
INTRODUCTION: Healthcare systems worldwide face unprecedented challenges, including escalating costs, workforce shortages, and access disparities, which threaten their sustainability. The WHO projects an 18 million healthcare worker deficit by 2030, ... read more
Red blood cell distribution width (RDW)-derived indicators have increasingly been recognized as biomarkers reflecting systemic inflammation and hematological disorders. However, the prognostic value of these indicators in critically ill patients with... read more
Laryngoscope investigative otolaryngology
May 11, 2026
BACKGROUND: Large language models (LLMs), such as ChatGPT, are increasingly utilized by physicians for clinical decision support due to their ease of use and versatility. However, their performance in diagnostic imaging remains largely untested. This... read more
BACKGROUND: Testing for Blood-Borne-Viruses (BBVs) such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) is generally focused on specialist settings. However, people with undiagnosed infections are also p... read more
OBJECTIVE: To compare tuned end-to-end and hybrid deep learning strategies for image-based classification of common oral conditions under small and imbalanced data conditions, and to determine whether the same pattern persists in a clinically focused... read more
BACKGROUND: Chikungunya continues to expand geographically, driving demand for trustworthy, easy-to-read public guidance. Conversational AI systems are increasingly used for health information, yet their medical validity, reliability, and readability... read more
BMC medical informatics and decision making
May 11, 2026
Early non-invasive prediction of cardiovascular risk is an essential prerequisite for preventive medicine, especially in resource-limited settings. Retinal imaging provides unique insights into systemic vascular health; however, most existing deep le... read more
BACKGROUND: Post-stroke aphasia is a prevalent and often disabling language impairment. Despite its high incidence, the neuropathological mechanisms underlying post-stroke aphasia and the neural substrates of functional recovery remain poorly underst... read more
BACKGROUND: This study aimed to develop and internally validate an explainable machine-learning model using routinely available clinicopathologic and laboratory variables for predicting 3-year overall survival (OS) after radical cystectomy. METHODS: ... read more
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