AI Medical Compendium

A machine learning-based megakaryocyte identification system uncovers resident organs, markers, and functional diversity.

Developmental cell May 11, 2026

The organ- and stage-specific diversity of megakaryocytes (MKs) has prompted a reassessment of their distribution and functions. By integrating single-cell transcriptomic data across multiple organs and developmental stages, we identified previously ... read more

RegVelo: Gene-regulatory-informed dynamics of single cells.

Cell May 11, 2026

Cell fate transitions are driven by regulatory circuitry, yet RNA velocity models cellular dynamics without explicitly accounting for gene regulatory interactions, limiting mechanistic insight. Conversely, gene regulatory network (GRN) inference meth... read more

Microbial biosynthesis of stilbenoids: A comprehensive review.

Biotechnology advances May 11, 2026

Stilbenoids represent a valuable class of plant polyphenols with significant pharmacological activities, such as anticancer, anti-inflammatory, and antioxidant effects, leading to a growing market demand. Traditional plant extraction or chemical synt... read more

Bridging innovation and implementation in laboratory medicine: insights from a global survey on unmet needs and emerging technologies.

Clinica chimica acta; international journal of clinical chemistry May 11, 2026

Technological innovation in laboratory medicine is advancing rapidly, driven by artificial intelligence, next-generation sequencing, high-resolution mass spectrometry, novel biomarkers, and decentralized point-of-care testing. However, the translatio... read more

Tubulointerstitial Diseases: An Updated Framework for Diverse and Emerging Entities.

Kidney international May 11, 2026

Tubulointerstitial diseases represent a heterogeneous group of kidney diseases with diverse causes and overlapping histopathologic and immunophenotypic patterns. Unlike glomerular disease, tubulointerstitial diseases have lacked specificity and stand... read more

Engineering immune cells for next-generation therapies.

Journal of controlled release : official journal of the Controlled Release Society May 11, 2026

Immune cell engineering has emerged as a transformative frontier in medicine, reshaping therapeutic strategies for cancer, autoimmunity and infectious diseases. Advances in delivery technologies such as viral vectors, lipid nanoparticles and polymer-... read more

Screening of new detection targets and virulence factors in Cronobacter using pan-genome and machine learning.

Journal of microbiological methods May 11, 2026

Cronobacter species are emerging foodborne pathogens, and species identification is essential because the virulence of different species is diverse, with Cronobacter sakazakii (C. sakazakii) being the most virulent. This study aimed to mine new molec... read more

The relationship between intrinsic capacity and functional ability - identifying key environmental features to support healthy ageing.

Experimental gerontology May 11, 2026

BACKGROUND: Within the World Health Organization's (WHO) healthy ageing framework, older adult's functional ability (FA) is determined by the intrinsic capacity (IC), the living environment, and their interaction. This study aimed to identify candida... read more

DeepEpiX: a software for visualization, annotation and automatic epileptical spike detection in MEG recordings.

Journal of neuroscience methods May 11, 2026

BACKGROUND: Magnetoencephalography (MEG) non-invasively records brain activity. It is widely used in presurgical evaluation of drug-resistant epilepsy, where it contributes to localizing the epileptogenic zone. Manual analysis of MEG is time-consumin... read more

Integrated Prediction of Ceftriaxone Resistance in Major Salmonella Serotypes Using MALDI-TOF MS Data with Balanced Datasets and Machine Learning.

International journal of antimicrobial agents May 11, 2026

OBJECTIVES: Salmonella causes gastroenteritis and invasive infections worldwide, and rising ceftriaxone resistance complicates empirical therapy. Conventional culture-based susceptibility testing remains reliable but time-consuming. MALDI-TOF MS, wid... read more

Artificial Intelligence Medical Compendium