AI Medical Compendium

Integrated Prediction of Ceftriaxone Resistance in Major Salmonella Serotypes Using MALDI-TOF MS Data with Balanced Datasets and Machine Learning.

International journal of antimicrobial agents May 11, 2026

OBJECTIVES: Salmonella causes gastroenteritis and invasive infections worldwide, and rising ceftriaxone resistance complicates empirical therapy. Conventional culture-based susceptibility testing remains reliable but time-consuming. MALDI-TOF MS, wid... read more

From Tarsal Anatomy to Tear-Film Homeostasis: A History-Informed Review of the Meibomian Gland in Ocular Surface Biology.

Experimental eye research May 11, 2026

The meibomian gland was anatomically described in 1666, but its central role in ocular surface disease emerged only after tear-film physiology, in vivo imaging, lipid biochemistry, and consensus nosology converged. This review reconstructs the transi... read more

Decoding Parkinson's progression: A multi-modal SuStaIn ensemble approach validated on real-world PPMI data.

Neurobiology of disease May 11, 2026

BACKGROUND: Parkinson's disease (PD) exhibits substantial heterogeneity in clinical presentation and longitudinal progression, complicating prognosis, trial design, and precision therapeutics. While the Subtype and Stage Inference (SuStaIn) algorithm... read more

AI-Driven Discovery of an Allosteric Thrombin-Targeting Anticoagulant Peptide from Traditional Chinese Medicine Dilong (Pheretima aspergillum).

Journal of ethnopharmacology May 11, 2026

ETHNOPHARMACOLOGICAL RELEVANCE: Dilong, the dried body of Pheretima aspergillum, is a classic traditional Chinese medicine that has been clinically used for millennia to promote blood circulation and resolve blood stasis. Modern pharmacological studi... read more

Three-dimensional chromatin architecture in crustaceans: Emerging evidence, structural principles, and future directions: A review.

International journal of biological macromolecules May 11, 2026

Three-dimensional (3D) chromatin architecture is a fundamental regulatory layer for linking hierarchical chromatin organization to gene expression and phenotypic traits. While spatial genome biology is well-established in vertebrates and some model i... read more

RIMGOGraph: integrating AlphaFold-derived residue interaction graphs and protein language embeddings for structure-informed protein function prediction.

International journal of biological macromolecules May 11, 2026

Accurate protein function annotation remains a major challenge in computational biology because the growth of protein sequence and structural databases continues to outpace experimental characterization. Recent advances in structure prediction, parti... read more

Using natural language processing to assess proxy measures of therapeutic alliance across suicide risk tiers.

Journal of affective disorders May 11, 2026

Therapeutic alliance is a core predictor of psychotherapeutic outcome, in general, and suicide prevention, specifically. Although clinical literature suggests that maintaining positive alliance with high-suicide-risk patients can be particularly chal... read more

Artificial Intelligence Versus Electrophysiologist Adjudication of Atrial Arrhythmias.

Heart rhythm May 11, 2026

Exploring the Bone-Vascular Axis: AI-Augmented Chest CT Analysis in COPD Highlights Association Between Vertebral Bone Density and Arterial Calcifications.

Respiratory medicine May 11, 2026

OBJECTIVES: Artificial intelligence (AI) tools enable automated assessment of vertebral bone mineral density (BMD), coronary artery calcification (CAC), and aortic calcification on CT scans, offering multimorbidity analysis in chronic obstructive pul... read more

Identifying potential relationships between air pollutants and neutrophil extracellular traps formation in metabolic dysfunction-associated fatty liver disease by integrating computational toxicology and multi-omics data.

Environmental pollution (Barking, Essex : 1987) May 11, 2026

Metabolic dysfunction-associated fatty liver disease (MASLD) is a highly prevalent liver condition with a complex etiology increasingly linked to air pollution. However, the molecular mechanisms through which air pollutants exacerbate MASLD remain po... read more

Artificial Intelligence Medical Compendium