European journal of drug metabolism and pharmacokinetics
May 10, 2026
BACKGROUND AND OBJECTIVE: Valproic acid is a classic antiepileptic drug; however, it is characterized by a narrow therapeutic window, limited safety margin, and marked individual variability. Therapeutic drug monitoring has become a key approach for ... read more
Journal of cancer research and clinical oncology
May 10, 2026
PURPOSE: To investigate whether perioperative resting energy expenditure (REE) dynamics improve prediction of postoperative complications after gastrectomy for gastric cancer. METHODS: We retrospectively analyzed 193 patients who underwent elective g... read more
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
May 10, 2026
Spatial transcriptomics provides high-throughput measurement of gene expression while retaining spatial context; however, inferring accurate cell-type compositions within individual spots remains a major challenge. Here, we present STAID, a unified f... read more
Drug development and industrial pharmacy
May 10, 2026
SignificanceThe review aims to systematically explore the transformative impact of artificial intelligence (AI) on pharmaceutical sciences. It Address key research questions regarding how AI accelerates drug development, enhances clinical trial desig... read more
Under global climate change, sand and dust storms (SDS) in Northern China have exhibited new spatiotemporal evolution characteristics. To investigate SDS driving mechanisms, this study integrated multi-source remote sensing and reanalysis data (2005-... read more
Methane (CH4) is a significant greenhouse gas linked to key climate change drivers, garnering heightened global focus. However, existing CH4 risk management approaches lack spatial coordination for basin systems. Here, we combined hydrological simula... read more
Metropolises are confronted with ecosystem degradation driven by rapid urbanization and continuously intensified human activities, posing significant challenges to human well-being and urban sustainable development. Identifying the trade-offs and syn... read more
Journal of bioscience and bioengineering
May 10, 2026
Non-invasive analysis of spheroid quality was essential because spheroids better recapitulated in vivo-like cell-cell and cell-extracellular matrix (ECM) interactions than two-dimensional cultures. However, routine non-invasive methods to assess inte... read more
Artificial intelligence (AI) has vast potential to reshape nuclear medicine. Applications can be found at every step of the processing workflow, including image acquisition, image reconstruction, enhancement, and registration, segmentation, extractio... read more
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