Single-cell RNA sequencing (scRNA-seq) has transformed our ability to resolve cellular heterogeneity, but extracting meaningful signals remains challenging due to technical noise and batch effects. Most methods for denoising scRNA-seq data have focus... read more
Objective: To describe the ophthalmic examination protocol within the German National Cohort (NAKO) / NAKO Gesundheitsstudie, to report the baseline profile of participants undergoing ophthalmological assessment, and to illustrate the potential of th... read more
Background The integration of artificial intelligence (AI) in cardiology requires healthcare worker acceptance for successful implementation. Understanding attitudes and educational needs is crucial for developing effective training programs. Methods... read more
Large language models in clinical and educational settings routinely receive user-provided context containing incorrect prior beliefs. Existing benchmarks measure aggregate susceptibility to such priors but do not disentangle which structural compone... read more
Background: Bipolar disorder (BD) is frequently underdiagnosed, particularly in patients presenting with depressive disorders, leading to delays in appropriate treatment. Artificial intelligence (AI) applied to electronic health records (EHRs) may im... read more
Characterizing the dynamic coordination of distributed brain regions during cognitive tasks remains challenging, as traditional fMRI analysis focuses on localized activations without revealing the underlying information flow that drives them. Here, w... read more
High-throughput affinity-based proteomics has advanced biomedical research, yet fundamental, persistent discordance between mainstream platforms (SomaScan and Olink) routinely undermines the replication of findings. This platform-driven non-replicati... read more
High-resolution postmortem (ex vivo) magnetic resonance imaging enables detailed examination of brain anatomy at spatial scales not achievable in vivo and provides a unique opportunity to link morphometric measurements with the underlying pathology. ... read more
The application of transcranial magnetic stimulation (TMS) to lateral parietal cortex has shown promise in improving episodic memory in older adults with Mild Cognitive Impairment (MCI). Previous work has suggested that such improvements are achieved... read more
Manual colony counting remains the rate-limiting, operator-dependent step in culture-based food microbiology quality control (QC). Automated colony analysis using machine learning (ML) offers the potential to standardise, accelerate, and improve the ... read more
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.