Background: Large language models (LLMs) are increasingly used in medical education and clinical decision-making, but their reliability in high-risk medication dosing remains unclear. Opioid rotation is a common task requiring precise calculations wh... read more
Imaging genetics aims to understand how genetic variation influences brain structure and cognitive function. Traditional approaches often rely on imaging-derived phenotypes (IDPs), which require high-dimensional brain images to be reduced to predefin... read more
Aim: Exercise capacity is a powerful predictor of cardiovascular risk. In patients unable to exercise, body composition analysis can potentially be used to estimate cardiorespiratory fitness. We developed a body composition fitness score, then valida... read more
Accurate brain and cerebrospinal fluid (CSF) volume assessment is essential for pediatric hydrocephalus management. Current clinical practice relies on linear measurements that fail to capture complex three-dimensional ventricular morphology, while q... read more
Background. Commercial dental artificial intelligence in 2026 is overwhelmingly diagnostic: caries, calculus, periapical, and bone-level detection on radiographs. The clinically harder question that follows every diagnosis-given a patient's chart and... read more
Phylodynamics bridges the gap between epidemiology and pathogen genetic data by estimating epidemiological parameters from time-scaled pathogen phylogenies. Multi-type birth-death (MTBD) models are phylodynamic analogies of compartmental models in cl... read more
Understanding the genetic basis of human adaptation to environmental pressures is a central question in evolutionary biology. Recent advancements in genome-environment association (GEA) methods have provided novel insights into how genetic variation ... read more
BACKGROUND: Against the backdrop of increasing patient volumes, rising case complexity, and physicians' limited time, AI-driven systems for anamnesis, triage, and documentation offer substantial potential for efficiency gains in medical history takin... read more
Chloride transport-related proteins play critical roles in coordinating ion cycling, maintaining cellular homeostasis, and enabling plants to dynamically adapt to environmental changes, particularly under salt stress conditions. Given the rapid accum... read more
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