Large language models (LLMs) are increasingly deployed as agents for scientific discovery, but standardized frameworks for evaluating their performance and behaviour in scientific workflows are lacking. Protein design provides a demanding test case b... read more
Clinical adoption of machine learning (ML) in medical imaging is limited by the lack of interpretability. To address this, we present understandable post-hoc artificial intelligence reports (UPhAIR), a pipeline designed to generate transparent, evide... read more
Introduction: Adolescents with mental health disorders represent a vulnerable group with complex care needs, yet their and their relatives experiences in acute inpatient mental health services remain poorly understood. While patient-reported experien... read more
Background: Large language models (LLMs) are increasingly used in medical education and clinical decision-making, but their reliability in high-risk medication dosing remains unclear. Opioid rotation is a common task requiring precise calculations wh... read more
Imaging genetics aims to understand how genetic variation influences brain structure and cognitive function. Traditional approaches often rely on imaging-derived phenotypes (IDPs), which require high-dimensional brain images to be reduced to predefin... read more
Aim: Exercise capacity is a powerful predictor of cardiovascular risk. In patients unable to exercise, body composition analysis can potentially be used to estimate cardiorespiratory fitness. We developed a body composition fitness score, then valida... read more
Accurate brain and cerebrospinal fluid (CSF) volume assessment is essential for pediatric hydrocephalus management. Current clinical practice relies on linear measurements that fail to capture complex three-dimensional ventricular morphology, while q... read more
Background. Commercial dental artificial intelligence in 2026 is overwhelmingly diagnostic: caries, calculus, periapical, and bone-level detection on radiographs. The clinically harder question that follows every diagnosis-given a patient's chart and... read more
Phylodynamics bridges the gap between epidemiology and pathogen genetic data by estimating epidemiological parameters from time-scaled pathogen phylogenies. Multi-type birth-death (MTBD) models are phylodynamic analogies of compartmental models in cl... read more
Predicting transitions between health, disease, and death across biological systems remains an important challenge with significant implications for both ecological management and medical intervention. Although the principles underlying these transit... read more
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.