The sense of smell remains poorly understood, especially in contrast to visual and auditory coding. At the core of our sense of smell is the olfactory information flow, in which odorant molecules activate a subset of our olfactory receptors and combi... read more
The neuromodulator acetylcholine has been suggested to govern learning under uncertainty. Here, we investigated the role of muscarinic acetylcholine receptors in reward-guided learning and decision making under different degrees of uncertainty. We ad... read more
Predicting the anatomical site of metastasis from a primary tumour remains an unsolved problem in breast cancer (BRCA) and metastatic disease more broadly. The difficulty is structural: metastatic biology is multi-site (bone, lung, liver, brain), mul... read more
Background CLN3 disease, also known as juvenile neuronal ceroid lipofuscinosis, is a rare and neurodegenerative disorder characterized by the accumulation of lipopigments in the cells, progressive cognitive decline, seizures, and vision loss. Biomark... read more
Neuroectoderm-derived tissues are highly metabolically active and exhibit minimal regenerative turnover, rendering them uniquely vulnerable to age-related stress while preserving undiluted degenerative signals. Yet aging dynamics in these tissues rem... read more
Medication adherence among patients with diabetes remains suboptimal in low and middle income countries, including Nigeria. Emerging digital health interventions such as AI powered virtual support may be associated with improved adherence behaviours.... read more
Objectives To describe the design, operational safeguards, and early use of ChatIBD, a specialty-specific generative AI platform for inflammatory bowel disease (IBD), during its first 6 months of live deployment. Methods ChatIBD is an online question... read more
Tau protein aggregation in the brain is a hallmark of Alzheimer's disease (AD). Positron emission tomography (PET) is the only in vivo method to visualize tau pathology and estimate both its burden and regional distribution, but the use of tau-PET is... read more
Distinct smartphone interaction behaviors, like short-form video scrolling and mobile gaming, elicit qualitatively different cognitive and physiological responses. However, such distinctions is often overlooked by approaches that treat smartphone use... read more
This study aims to predict human intentions during intense sports activities, specifically in table tennis. Using a publicly available Real World Table Tennis dataset containing simultaneous EEG and video recordings, we developed a series of particip... read more
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