AI Medical Compendium

IHM-DDI: Integrating High-order Interaction Topology and Morgan Fingerprint Features for Drug-Drug Interaction Prediction.

Analytical biochemistry May 7, 2026

Drug-drug Interaction (DDI) prediction is crucial in pharmacology and clinical applications. Conventional methods remain constrained by single-view paradigms, limiting multi-source data fusion and cross-view synergistic learning critical for comprehe... read more

Artificial intelligence in certification examinations: a CBIC-informed perspective for infection prevention and control.

American journal of infection control May 7, 2026

Benign-by-design chemistry: Reinventing ligand-based drug design at the edge of AI.

Drug discovery today May 7, 2026

Ligand-based drug design (LBDD) has long driven therapeutic innovation; however, its traditional potency-centered paradigm often oversimplifies biological complexity. Advances in artificial intelligence (AI) now enable multiobjective strategies that ... read more

Disproportionately Elevated Sulcal Index (DESI): An automatically driven index representing disproportionate subarachnoid space enlargement in brain MRI scans.

Brain research bulletin May 7, 2026

INTRODUCTION: Idiopathic normal pressure hydrocephalus (iNPH) is frequently underdiagnosed due to non-specific symptoms and the risks of invasive testing. While disproportionately enlarged subarachnoid space hydrocephalus (DESH) is a hallmark imaging... read more

Emerging Therapeutic Paradigms in Tuberculosis: Nanocarriers, Host-Directed Strategies, and Translational Pharmacology.

Microbial pathogenesis May 7, 2026

TB remains a significant global health burden due to protracted therapeutic courses, poor patient compliance, and toxicities associated with drug treatment, as well as concerns arising from increasingly prevalent multidrug-resistant and extensively d... read more

Thrombosis at the crossroads of inflammation, coagulation, and vascular biology: Recent advances and emerging therapeutic strategies.

Clinica chimica acta; international journal of clinical chemistry May 7, 2026

Thrombosis is a multifaceted pathological process involving intravascular clot formation that drives a range of cardiovascular and cerebrovascular diseases, including myocardial infarction, ischemic stroke, venous thromboembolism, and cancer-associat... read more

Quantum-Enabled Approaches to Precision Nutrition: Linking Molecular Interactions with Metabolic Prediction.

The Journal of nutrition May 7, 2026

Precision nutrition aims to tailor dietary guidance to individual biology, yet current methods struggle to integrate complex molecular and multi-omic data into clinical care. Emerging quantum-driven technologies encompassing quantum computing, quantu... read more

Astaxanthin biomanufacturing under hierarchical constraints: Integrating synthetic biology and artificial intelligence for scalable production.

Biotechnology advances May 7, 2026

Astaxanthin is a high-value ketocarotenoid of growing industrial importance; however, its scalable biomanufacturing is constrained by inherent biological complexity. Production performance is governed by hierarchical constraints, including molecular ... read more

A structured oral formulation database for machine learning: Uncovering data-informed design strategies to facilitate effective formulation development.

International journal of pharmaceutics May 7, 2026

Oral dosage form development still relies heavily on empirical trial-and-error, while the high prevalence of poorly soluble drug candidates increases the need for structured data support. To address this limitation, we constructed the Computational P... read more

Mapping mosquito flight dynamics and directional responses: A scalable deep learning model for behavioural research.

Acta tropica May 7, 2026

Mosquitoes are important vectors of pathogens that affect millions of people worldwide. Understanding their flight patterns and behaviours is crucial for developing novel control and surveillance tools. Mosquito flight track analysis using traditiona... read more

Artificial Intelligence Medical Compendium