Large language models are increasingly deployed in clinical decision-support contexts, yet systematic evaluation of their factual reliability in generating patient-specific diagnostic reports remains sparse, particularly for laboratory interpretation... read more
The emergence of unidentified pathogens, or "Disease X," poses a significant threat to global health, necessitating the development of proactive surveillance strategies for the wildlife and human virosphere. Since novel viruses often lack universal g... read more
Genomic prediction (GP) across diverse environments has a potential to accelerate genetic gain in cotton breeding programs. A major challenge in GP is modelling genotype-by-environment interactions (GEI), which is essential for selecting stable and h... read more
Cellular reprogramming is a complex interplay between perturbations and regulatory elements, culminating in gene expression changes. Current computational approaches do not explicitly model these regulatory interactions. Here, we first performed comb... read more
Objective: We surveyed 524 healthcare professionals (HCPs) in the United States and United Kingdom to examine workplace generative AI use, access, and barriers in two high-maturity health settings. Methods: This cross-sectional survey compared AI usa... read more
ABSTRACT Objectives: To determine whether heterogeneous treatment effects (HTE) explain the inconclusive results of targeted temperature management (TTM) trials after cardiac arrest, using causal machine learning across four datasets. Design: Seconda... read more
Abstract Objective: Structured extraction from clinical free-text depends on human annotators whose labels are susceptible to errors and knowledge-driven mistakes; exhaustive quality control is impractical at scale. We evaluate whether disagreement a... read more
Rare diseases are characterized by heterogeneous, weak, and sparse phenotypic signals that emerge gradually across longitudinal clinical visits, making early detection a persistent challenge. In this study, we propose a hierarchical set-to-sequence (... read more
Abstract Objective: Conventional pharmacodynamic (PD) modeling workflows require manual model selection, repeated equation rewriting, and empirical parameter adjustment, resulting in limited automation, high cross-scenario migration costs, and insuff... read more
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