AI Medical Compendium

Multi-cohort proteogenomic analyses reveal genetic effects across the proteome and diseasome.

Cell May 6, 2026

Understanding the genetic regulation of circulating protein levels can provide new insights into disease mechanisms. Here, we present the largest proteogenomic study to date (n = 78,664 participants across 38 studies), identifying >24,000 protein qua... read more

Towards structure-aware surrogate modeling: explicit region interaction improves knee contact stress prediction in young men.

Journal of biomechanics May 6, 2026

Knee contact-stress hotspots are closely linked to meniscal/cartilage injury risk. Still, high-fidelity subject-specific FEA is too computationally expensive for large-cohort, multi-condition, near-real-time use. Existing MeshGraphNet (MGN)-style sur... read more

Artificial Intelligence-based smartphone application for real-time blinking assessment.

The ocular surface May 6, 2026

Next-generation gene editing strategies in cancer: Integrating CRISPR, PROTACs, and advanced molecular technologies.

Life sciences May 6, 2026

Cancer is a significant therapeutic problem as tumors are heterogeneous, multidrug-resistant, and oncogenic drivers are undruggable. Genome editing and targeted protein degradation are emerging approaches that are transforming precision oncology by a... read more

Advances in neuropharmacology: Innovative drug strategies targeting synaptic plasticity, neuroinflammation, and ion channel regulation for future CNS treatments.

Life sciences May 6, 2026

As our understanding of the molecular and cellular mechanisms underlying central nervous system (CNS) disorders expands, neuropharmacology is undergoing a paradigm shift. Despite the increasing burden of neurodegenerative and neuropsychiatric disease... read more

Pathophysiological mechanisms of High-Pressure Nervous Syndrome: A Comprehensive review.

Neuroscience May 6, 2026

High-Pressure Nervous Syndrome (HPNS) refers to a series of neurological disturbances that occur during exposure to high hydrostatic pressure, characterized by cognitive and motor impairment manifestations. This review systematically summarizes the r... read more

CellXpress.ai: Machine learning powered system for automation of complex 2D and 3D cell culture workflows.

SLAS technology May 6, 2026

Attrition in the therapeutic pipeline can often be attributed to a lack of translational efficacy from pre-clinical to clinical phases. Organoids show great promise as a game-changer in disease modeling and drug screening, as they better resemble tis... read more

Mechanistically Informed and Omics-Guided Essential Oil Applications for Food Preservation.

Journal of food protection May 6, 2026

The growing demand for safe, sustainable, and clean-label food preservation strategies has accelerated interest in plant-derived essential oils (EOs) as natural antimicrobial agents. These chemically complex mixtures exhibit broad-spectrum activity a... read more

Psyche and pixels: AI-generated images and their impact on stigma of mental illnesses in Germany.

Journal of psychiatric research May 6, 2026

Artificial intelligence (AI) has rapidly evolved in recent years. Image generating chatbots enjoy great popularity. But they bear the risk of maintaining or enhancing preexisting stereotypes and stigma against severe mental illnesses. The objective o... read more

Prevalence and determinants of sacroiliac joint bone marrow oedema in the general population in Germany: a population-based cross-sectional study.

The Lancet. Rheumatology May 6, 2026

BACKGROUND: MRI-detected bone marrow oedema in sacroiliac joints is central to diagnosing axial spondyloarthritis, influencing treatment decisions including anti-inflammatory therapy initiation. However, the prevalence of bone marrow oedema in the ge... read more

Artificial Intelligence Medical Compendium